36635-56-0Relevant articles and documents
Br?nsted Acid Organocatalyzed Three-Component Hydroamidation Reactions of Vinyl Ethers
Smajlagic, Ivor,Carlson, Brenden,Dudding, Travis
, p. 4171 - 4181 (2021)
Hydroamidation of carbon-carbon double bonds is an attractive strategy for installing nitrogen functionality into molecular scaffolds and, with it, increasing molecular complexity. To date, metal-based approaches have dominated this area of chemical synth
Phenyl pyrrole compound and application thereof in bactericidal activity
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Paragraph 0137; 0139, (2020/08/17)
The invention provides a novel phenyl pyrrole compound, and the phenyl pyrrole compound shows good bactericidal activity and can be used for preparing a broad-spectrum plant bactericide. In addition,the synthesis route is simple, the operation is convenient, the synthesis cost is reduced, and ecological environment pollution to soil, surface water, underground water and the like is avoided.
A 2-fluoro-4-methyl sulfonyl methyl isonitriles method for the synthesis of
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Paragraph 0021; 0022, (2017/03/08)
The invention discloses a synthesis method of 2-fluoro-4-toluenesulfonylmethyl isocyanide. The method comprises the following steps: with sodium p-tolylsulfinate as a raw material, carrying out similar Mannich condensation and amide dehydration reaction to prepare tolylsulfonylmethyl isocyanide; adding a hydrofluoric acid aqueous solution and an Ni-CO catalyst to tolylsulfonylmethyl isocyanide; and fully reacting under nitrogen protection, and carrying out suction filtration, washing and drying to obtain faint yellow crystal 2-fluoro-4-toluenesulfonylmethyl isocyanide, wherein the yield reaches over 92%, and the purity is 99.8%. The synthesis method has the advantages of being available in reaction raw materials, mild in condition, high in yield, suitable for industrial production and the like.
