36724-27-3

Basic information

• Product Name: 3-butylbenzo[b]-furan
• Synonyms: 3-butylbenzo[b]-furan
• CAS NO: 36724-27-3
• Molecular Weight: 174.243
• Mol File: 36724-27-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-butylbenzo[b]-furan(CAS DataBase Reference)
• NIST Chemistry Reference: 3-butylbenzo[b]-furan(36724-27-3)
• EPA Substance Registry System: 3-butylbenzo[b]-furan(36724-27-3)

Safety Data

• Hazardous Substances Data: 36724-27-3(Hazardous Substances Data)

Upstream product

• 1248340-86-4 1-chloro-2-(2-hydroxyphenyl)-hexan-2-ol 

Relevant articles and documents

Controlled synthesis of 2-and 3-substituted benzo[ b ]furans

A controlled regioselective synthesis of either C-2 or C-3 substituted benzo[b]furans from readily accessible 1-(2-hydroxyphenyl)-2-chloroethanones is described. Addition of a range of Grignard reagents to the α-chloro ketones generates alkoxide intermediates, which can form either 2-substituted benzo[b]furans via a [1,2]-aryl migration or 3-substituted benzo[b]furans via a direct cyclization and dehydration sequence. A temperature-dependent [1,2]-aryl migration mechanism for the formation of 2-substituted benzo[b]furan is proposed.