36740-10-0

Basic information

• Product Name: 4-OXO-4-PYRIDIN-3-YLBUTANENITRILE
• Synonyms: 3-pyridinebutanenitrile, gamma-oxo-; 4-Oxo-4-(3-pyridinyl)butanenitrile; 4-Oxo-4-(3-pyridinyl)butanonitril; 4-Oxo-4-(pyridin-3-yl)butanenitrile; 4-oxo-4-pyridin-3-ylbutanenitrile
• CAS NO: 36740-10-0
• Molecular Formula: C₉H₈N₂O
• Molecular Weight: 160.1726
• Mol File: 36740-10-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 370°Cat760mmHg
• Flash Point: 177.5°C
• Appearance: /
• Density: 1.139g/cm³
• Vapor Pressure: 1.14E-05mmHg at 25°C
• Refractive Index: 1.531
• CAS DataBase Reference: 4-OXO-4-PYRIDIN-3-YLBUTANENITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-OXO-4-PYRIDIN-3-YLBUTANENITRILE(36740-10-0)
• EPA Substance Registry System: 4-OXO-4-PYRIDIN-3-YLBUTANENITRILE(36740-10-0)

Safety Data

• Hazardous Substances Data: 36740-10-0(Hazardous Substances Data)

Usage

General Description

4-OXO-4-PYRIDIN-3-YLBUTANENITRILE is a chemical compound with the molecular formula C9H7N3O. It is a pyridine derivative with a butanenitrile group and a ketone functional group. 4-OXO-4-PYRIDIN-3-YLBUTANENITRILE is used in organic synthesis and as a building block for the preparation of various pharmaceuticals and agrochemicals. It is also used in the manufacturing of dyes and other chemical products. 4-OXO-4-PYRIDIN-3-YLBUTANENITRILE is a versatile compound with a range of potential applications in the chemical, pharmaceutical, and agricultural industries.

InChI:InChI=1/C9H8N2O/c10-5-1-4-9(12)8-3-2-6-11-7-8/h2-3,6-7H,1,4H2

Upstream product

• 104501-58-8 1-Trimethylsilyloxy-1-(3-pyridyl)-ethene 
• 350-03-8 methyl-3-pyridylketone 
• 151-50-8 potassium cyanide 
• 6293-82-9 N,N-dimethyl-3-oxo-(3-pyridinyl)-1-propanamine hydrochloride 
• 500-22-1 3-pyridinecarboxaldehyde 
• 107-13-1 acrylonitrile 

Downstream Products

• 5746-86-1 rac-nornicotine 
• 532-12-7 Myosmine 

Relevant articles and documents

A PROCESS FOR THE PREPARATION OF NICOTINE

The present invention relates to a process for the preparation of racemic nicotine from 3- pyridylaldehyde using a one-pot or step-wise method. The process comprises the following steps: Stetter reaction, reduction-cyclisation and methylation.

Antibodies against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and metabolites thereof

The present invention relates to compounds, methods for their preparation, conjugates obtainable by coupling the compounds to immunogenic carriers, pharmaceutical compositions comprising the conjugates, the use of the conjugates for treating and/or preventing disorders associated with tobacco specific nitrosamine exposure, methods for the preparation of the conjugates, antibodies which can be obtained using the conjugates, a method for the preparation of the antibodies and a method of detecting 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a metabolite or an adduct comprising a pyridyloxobutyl group derived from NNK, wherein the antibodies are employed. The present invention also relates to a method of detecting antibodies specific for NNK, non-detoxified metabolites or the above adducts thereof, wherein the conjugates are employed.

A New Simple Synthesis of Fusaric Acid and Other 5-Alkyl-2-pyridinecarboxylic Acids

Carboxamido groups are introduced into the 6-position of 3-acylpyridines with high regioselectivity via Minisci reaction with formamides, Fe(II) sulfate and tert-butyl hydroperoxide.The isolation procedure is considerably improved by the addition of citric acid for complexation of the Fe ions.Fusaric acid and other 5-alkyl-2-pyridine carboxylic acids are obtained by a following Wolff-Kishner reaction in 20-75percent overall yield.