36746-26-6 Usage
Description
6-amino-5-nitropyrimidin-4(1H)-one is a chemical compound characterized by the molecular formula C4H3N5O3. It is a yellow solid with a melting point of 272-274 °C. 6-amino-5-nitropyrimidin-4(1H)-one is recognized for its role in organic synthesis and pharmaceutical research, where it serves as a building block for the preparation of various biologically active molecules. Its structure and properties have positioned it as a valuable tool in the field of medicinal chemistry and drug discovery, with potential applications in the development of new drugs and as a key intermediate in the synthesis of pharmaceuticals and fine chemicals.
Uses
Used in Pharmaceutical Research:
6-amino-5-nitropyrimidin-4(1H)-one is used as a building block for the synthesis of biologically active molecules, contributing to the development of new drugs. Its unique structure allows it to be a key intermediate in the creation of pharmaceuticals and fine chemicals, enhancing the diversity and effectiveness of available treatments.
Used in Organic Synthesis:
In the field of organic synthesis, 6-amino-5-nitropyrimidin-4(1H)-one is utilized as a versatile component in the preparation of complex organic compounds. Its reactivity and stability make it suitable for a wide range of chemical reactions, facilitating the synthesis of various organic molecules with potential applications in different industries.
Used in Medicinal Chemistry:
6-amino-5-nitropyrimidin-4(1H)-one is employed as a valuable tool in medicinal chemistry, where it aids in the discovery and optimization of drug candidates. Its properties enable researchers to explore new chemical spaces and design innovative therapeutic agents with improved pharmacological profiles.
Used in Drug Development:
In the development of new drugs, 6-amino-5-nitropyrimidin-4(1H)-one is used as a key intermediate, playing a crucial role in the synthesis of pharmaceuticals with potential therapeutic benefits. Its presence in the drug development pipeline underscores its importance in advancing the field of medicinal chemistry and contributing to the creation of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 36746-26-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,7,4 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 36746-26:
(7*3)+(6*6)+(5*7)+(4*4)+(3*6)+(2*2)+(1*6)=136
136 % 10 = 6
So 36746-26-6 is a valid CAS Registry Number.
36746-26-6Relevant articles and documents
Reducing the Electron Delocalization of FOX-7 toward a Thermally Stable Explosive as a Hexanitrosilbene (HNS) Replacement
Yin, Zhaoyang,Huang, Wei,Zeng, Zhiwei,Liu, Yuji,Tang, Yongxing
, p. 1867 - 1873 (2022/02/23)
Exploring derivatives of FOX-7 to improve the thermal stability has been an important project in the field of energetic materials. Creating vicinal nitro/amino arrangement and planar structure are the most common strategies used to improve the thermal stability of energetic materials. In this research, a carbonyl substituted vicinal nitro/amino pyrimidine (4) with planar structure was synthesized. It showed ultrahigh thermal stability with the onset decomposition temperature of 328 °C, which is higher than the commonly used heat-resistant explosive hexanitrosilbene (HNS) (Td= 322 °C). 4 also exhibited extremely low mechanical sensitivities, compared to these of HNS, which further guaranteed its application as an HNS replacement.