36838-04-7Relevant articles and documents
The phosphinoboration of acyl chlorides
Binder, Justin F.,Geier, Stephen J.,Lafortune, James H. W.,Macdonald, Charles L. B.,Murphy, Maia C.,Stephan, Douglas W.,Trofimova, Alina,Vogels, Christopher M.,Westcott, Stephen A.
, p. 5092 - 5099 (2020)
This investigation examines the reactivity of phosphinoboronate esters Ph2PBpin (pin = 1,2-O2C2Me4) and Ph2PBcat (cat = 1,2-O2C6H4), as well as other phosphinoboron species, with various aryl and aliphatic acyl chlorides. These reactions proceed smoothly to give acyl phosphines of the type RC(O)PR′2 along with loss of a boron-chloride compound. In some cases, a second equivalent of the phosphinoboron species can add to the CO double bond at elevated temperatures to give the corresponding diphosphines RC(OBR′′2)(PR′2)2. These ambiphilic diphosphines behave like substituted (1,1-bis(diphenylphosphino)methane) derivatives in a reaction of PhC(OBpin)(PPh2)2 (2a) with (η5-C9H7)Rh(η2-coe)2 (coe = cis-cyclooctene) affording the indenyl rhodium complex (η5-C9H7)Rh(PhC(OBpin)(PPh2)2) (3a) where the phosphines are bound to the metal centre in a κ2-P,P bidentate manner.
Continuous preparation method of trimethylbenzoyl-diphenylphosphine oxide compound
-
Paragraph 0035-0036, (2019/10/07)
The invention discloses a continuous preparation method of trimethylbenzoyl-diphenylphosphine oxide (TPO) and its derivatives. The preparation method comprises: in a tubular reactor, benzaldehyde or its derivative reacts with chlorodiphenyl phosphine or its derivative; and then a catalytic oxidation reaction is directly carried out without separation, and the reaction solution is desolvated and re-crystallized to obtain a TPO product. The conversion rate of the product TPO is 98% and above, and the finished product content reaches 99.5% and above.
Differentially Substituted Phosphines via Decarbonylation of Acylphosphines
Yu, Rongrong,Chen, Xingyu,Martin, Stephen F.,Wang, Zhiqian
, p. 1808 - 1811 (2017/04/11)
A new route to phosphines was developed by a method that features a "pre-join and transform" process that proceeds via acylphosphine intermediates that may be readily prepared from carboxylic acids and disubstituted phosphines. The efficient decarbonylations of these acylphosphines using a nickel catalyst delivered the corresponding phosphines. This method shows that the carboxyl group can play a role similar to halides or triflates for introducing a substituted phosphorus atom on an aromatic ring.
