368864-66-8

Basic information

• Product Name: 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-methyl-N-(4-piperidinyl)acetamide
• Synonyms: 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-methyl-N-(4-piperidinyl)acetamide
• CAS NO: 368864-66-8
• Molecular Weight: 319.447
• Mol File: 368864-66-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-methyl-N-(4-piperidinyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-methyl-N-(4-piperidinyl)acetamide(368864-66-8)
• EPA Substance Registry System: 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-methyl-N-(4-piperidinyl)acetamide(368864-66-8)

Safety Data

• Hazardous Substances Data: 368864-66-8(Hazardous Substances Data)

Upstream product

• 368865-12-7 2-[4-(tert-butoxycarbonylamino)-2,3,5,6-tetramethylphenoxy]acetic acid 
• 71760-04-8 propylphosphonic anhydride 

Downstream Products

• 787540-27-6 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-(1-cyclo-propylmethyl-4-piperidinyl)-N-methylacetamide 
• 761392-52-3 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-methyl-N-(1-phenethyl-4-piperidinyl)acetamide 
• 735257-30-4 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-[1-(2-anilino-2-oxoethyl)-4-piperidinyl]-N-methylacetamide 
• 750562-62-0 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-methyl-N-[1-(1-methyl-2-phenylethyl)-4-piperidinyl]acetamide 
• 760936-93-4 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-methyl-N-{1-[2-(N-methylanilino)-2-oxoethyl]-4-piperidinyl}acetamide 
• 775570-93-9 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-methyl-N-{1-[2-(4-morpholinyl)ethyl]-4-piperidinyl}acetamide 
• 754177-49-6 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-{1-[2-(2-hydroxy-2-phenylethoxy)ethyl]-4-piperidinyl}-N-methylacetamide 
• 715653-45-5 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-[1-(4-cyano-benzyl)-4-piperidinyl]-N-methylacetamide 
• 728862-19-9 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-methyl-N-{1-[2-(phenylthio)ethyl]-4-piperidinyl}acetamide 
• 779316-72-2 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-(1-butyl-4-piperidinyl)-N-methylacetamide 
• 691351-44-7 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-(1-benzoyl-4-piperidinyl)-N-methylacetamide 
• 749840-54-8 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-methyl-N-[1-(2-propynyl)-4-piperidinyl]acetamide 
• 777845-45-1 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-methyl-N-[1-(2-phenoxyethyl)-4-piperidinyl]acetamide 
• 743412-57-9 2-(4-Amino-2,3,5,6-tetramethylphenoxy)-N-[1-(2-phenyl-2-oxoethyl)-4-piperidinyl]-N-methylacetamide 

Relevant articles and documents

Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof

There is provided an aminophenoxyacetamide derivative of the formula (I): wherein, R1 to R4 are, independent from each other, hydrogen atom; optionally substituted alkyl group; E1 is —NR4— and E2 is oxygen atom or —NR10; Q is group —X—Y—Q′ (X and Y are connecting bond; X is alkylene or alkenylene group, etc.; Y is selected from the groups consisting of C═O, NHC(═O), C(═O)NH, etc.; Q′ is hydrogen atom or pheny, pyridyl groups which may be substituted, etc.), or a pharmaceutically acceptable salt thereof. These compounds have neuroprotective effect by introducing the CalbindinD-28k, one of Ca2+-binding proteins. 11