368866-07-3

Basic information

• Product Name: 4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-(9H-FLUOREN-9-YLMETHYL) ESTER
• Synonyms: N-(TERT-BUTOXYCARBONYL)-AMINO-(4-N-FMOC-PIPERIDINYL)CARBOXYLIC ACID;N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL) CARBOXYLIC ACID;BOC-4,4-ACP(1-N-FMOC);4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-(9H-FLUOREN-9-YLMETHYL) ESTER;4-[(TERT-BUTOXYCARBONYL)AMINO]-1-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]PIPERIDINE-4-CARBOXYLIC ACID;4-N-BOC-AMINO-(N-FMOC-PIPERDINYL)-4-CARBOXYLIC ACID;4-N-Boc-amino-(N-Fmoc-piperidinyl)-4-carboxylic acid;1,4-Piperidinedicarboxylicacid,4-[[(1,1-dimethylethoxy)carbonyl]amino]-,1-(9H-fluoren-9-ylmethyl)ester(9CI)
• CAS NO: 368866-07-3
• Molecular Formula: C₂₆H₃₀N₂O₆
• Molecular Weight: 466.53
• Product Categories: N-BOC;Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Heterocycles;amino acids
• Mol File: 368866-07-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 569.36°C (rough estimate)
• Flash Point: 351.8 °C
• Appearance: /
• Density: 1.2464 (rough estimate)
• Vapor Pressure: 3.23E-18mmHg at 25°C
• Refractive Index: 1.5300 (estimate)
• Storage Temp.: Freezer (-20°C)
• PKA: 3.85±0.20(Predicted)
• CAS DataBase Reference: 4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-(9H-FLUOREN-9-YLMETHYL) ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-(9H-FLUOREN-9-YLMETHYL) ESTER(368866-07-3)
• EPA Substance Registry System: 4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-(9H-FLUOREN-9-YLMETHYL) ESTER(368866-07-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• Hazardous Substances Data: 368866-07-3(Hazardous Substances Data)

Usage

Description

4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-(9H-FLUOREN-9-YLMETHYL) ESTER, also known as 4-(Boc-amino)-1-(Fmoc-piperidinyl)-4-carboxylic acid, is a chemical compound with the appearance of a white to off-white powder. It is characterized by its chemical structure that includes a piperidine ring with a carboxylic acid group at both ends, a tert-butoxycarbonyl (Boc) group, and a 9H-fluoren-9-ylmethyl (Fmoc) group. 4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-(9H-FLUOREN-9-YLMETHYL) ESTER is significant in the field of pharmaceuticals due to its potential applications in the development of therapeutic agents.

Uses

Used in Pharmaceutical Industry:
4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-(9H-FLUOREN-9-YLMETHYL) ESTER is used as a building block for the synthesis of peptide amides, specifically targeting the kappa opioid receptor agonists. These agonists are crucial in the treatment of pain, pruritis (itching), and inflammation associated with various diseases. 4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-(9H-FLUOREN-9-YLMETHYL) ESTER's unique structure allows for the development of potent and selective therapeutic agents that can effectively manage these conditions.

InChI:InChI=1/C26H30N2O6/c1-25(2,3)34-23(31)27-26(22(29)30)12-14-28(15-13-26)24(32)33-16-21-19-10-6-4-8-17(19)18-9-5-7-11-20(18)21/h4-11,21H,12-16H2,1-3H3,(H,27,31)(H,29,30)/p-1