37034-22-3Relevant articles and documents
Effect of enzymatic sulfation on biochemical and pharmacological properties of catecholamines and tyrosine-containing peptides
Konishi-Imamura,Kim,Kobashi
, p. 2994 - 2998 (1991)
Substrate specificity of a novel sulfotransferase produced by Eubacterium A-44 isolated from human feces has been studied. Phenolic drugs, catecholamines, were good acceptors of this bacterial enzyme. With regard to dopamine, sulfation mostly occurred at
Synthesis and biological studies of glycosyl dopamine derivatives as potential antiparkinsonian agents
Fernandez, Caridad,Nieto, Ofelia,Rivas, Emilia,Montenegro, Gisela,Fontenla, Jose A.,Fernandez-Mayoralas, Alfonso
, p. 353 - 365 (2007/10/03)
A new approach to deliver dopamine into the central nervous system, based on the use of D-glucose as transportable agent, has been studied. Glycosyl dopamine derivatives bearing the sugar moiety linked to either the amino group or the catechol ring of dopamine through amide, ester or glycosidic bonds were synthesised as potential antiparkinsonian agents. Studies on the binding to dopamine D2 receptor, in vitro stability, and locomotive effect in mice of the synthetic glycoconjugates are reported. Copyright (C) 2000 Elsevier Science Ltd.
O2-Cu2+-ASCORBIC ACID: A NOVEL OXIDATION SYSTEM FOR THE HIGHLY SELECTIVE O-DEALKYLATION OF 2-ALKOXYPHENOLS
Aihara, Kazuhiro,Higuchi, Tsunehiko,Hirobe, Masaaki
, p. 837 - 840 (2007/10/02)
The novel oxidation system "O2-Cu2+-ascorbic acid" is a selective reagent for the oxidative O-dealkylation of 2-alkoxyphenols and affords catechols in good yield.KEYWORDS - O-dealkylation; ascorbic acid; copper ion; oxidation; 2-alkoxyphenol; vanillin; dopamine; guaiacol; catechol