37051-05-1 Usage
Description
(6R-trans)-3-[(carbamoyloxy)methyl]-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a complex organic compound with a unique molecular structure. It is characterized by its bicyclic ring system, which includes a thiazole and an azabicyclo[4.2.0]oct-2-ene component. The molecule also features a carbamoyloxy group, an 8-oxo group, and a 2-thienylacetamido group, which contribute to its chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
(6R-trans)-3-[(carbamoyloxy)methyl]-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is used as an active pharmaceutical ingredient (API) for the development of new drugs. Its unique structure and functional groups make it a promising candidate for targeting specific biological pathways and receptors, potentially leading to the creation of novel therapeutic agents.
Used in Antibacterial Applications:
In the pharmaceutical industry, (6R-trans)-3-[(carbamoyloxy)methyl]-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is used as an antibacterial agent. It is an impurity of Cefoxitin (C243190), a semi-synthetic antibiotic derived from Cephamycin C, which is known for its high resistance to β-lactamase inactivation. (6R-trans)-3-[(carbamoyloxy)methyl]-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid contributes to the overall effectiveness of Cefoxitin in treating bacterial infections.
Used in Research and Development:
(6R-trans)-3-[(carbamoyloxy)methyl]-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is also used in research and development for various applications. Its unique chemical properties make it an interesting subject for studying its interactions with biological systems, potentially leading to the discovery of new therapeutic targets and drug candidates.
Check Digit Verification of cas no
The CAS Registry Mumber 37051-05-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,0,5 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 37051-05:
(7*3)+(6*7)+(5*0)+(4*5)+(3*1)+(2*0)+(1*5)=91
91 % 10 = 1
So 37051-05-1 is a valid CAS Registry Number.
InChI:InChI=1/C15H15N3O6S2/c16-15(23)24-5-7-6-26-13-10(12(20)18(13)11(7)14(21)22)17-9(19)4-8-2-1-3-25-8/h1-3,10,13H,4-6H2,(H2,16,23)(H,17,19)(H,21,22)/t10-,13-/m0/s1
37051-05-1Relevant articles and documents
Synthesis method of antibacterial drug cefoxitin
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, (2017/01/26)
The invention discloses a synthesis method of an antibacterial drug cefoxitin. The synthesis method comprises the following steps: taking 7-amino cephalosporanic acid as a raw material; adding a curing enzyme into an alkaline solution to hydrolyze; after hydrolyzing, filtering the curing enzyme; after adding ethyl acetate, starting to drop 2-thiophene acetylation reagent to react; after introducing thiophene acetyl, dropping a benzathine diacetate solution and separating out crystals to obtain a compound I; taking the compound I to react with an aminomethoxyl acylation reagent to react and introducing aminoformylmethoxyl at a site 3 of the compound I, so as to obtain a compound II; taking the compound II to react with tertiary-butyl hypochlorite and sodium methoxide to react to introduce methoxyl at a site 7 of the compound II to obtain the cefoxitin. The synthesis method has the advantages of low cost of raw materials, high yield, moderate reaction conditions, good powder crystallinity and small granularity of synthesized powder. The synthesis method needs simple equipment, has a simple reaction process, is easy to implement and is suitable for large-scale production.
