37067-52-0

Basic information

• Product Name: α,α-dichloromethyl p-tolyl sulfoxide
• Synonyms: α,α-dichloromethyl p-tolyl sulfoxide
• CAS NO: 37067-52-0
• Molecular Weight: 223.123
• Mol File: 37067-52-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: α,α-dichloromethyl p-tolyl sulfoxide(CAS DataBase Reference)
• NIST Chemistry Reference: α,α-dichloromethyl p-tolyl sulfoxide(37067-52-0)
• EPA Substance Registry System: α,α-dichloromethyl p-tolyl sulfoxide(37067-52-0)

Safety Data

• Hazardous Substances Data: 37067-52-0(Hazardous Substances Data)

Upstream product

• 934-72-5 Methyl p-tolyl sulfoxide 
• 14738-27-3 ethyl (p-tolylthio)acetate 
• 623-13-2 4-methylphenyl methylsulfide 

Relevant articles and documents

Resolution of racemic aryl dichloromethyl sulfoxides with (-)-menthone

The addition reaction of the sodium α-sulfinyl carbanion of a racemic aryl dichloromethyl sulfoxide to (-)-menthone in the presence of boron trifluoride diethyl etherate gave an adduct as a mixture of two easily separable diastereomers. After separation of the diastereomers, they were each treated with sodium hydride to afford enantiomerically pure aryl dichloromethyl sulfoxides and (-)-menthone both in high yields. This procedure provides a simple and efficient method for the resolution of racemic aryl dichloromethyl sulfoxides.

Asymmetric Synthesis of α,α-dichlorosulphoxides from Substituted Thioacetates and Sodium Hypochlorite in β-Cyclodextrin Complexes

The reaction of β-cyclodextrin complexes of substituted thioacetates (1) with sodium hypochlorite in aqueous medium gives optically active α,α-dichlorosulphoxides (2) in good yields with an enantiomeric excess (e.e.) of up to 53percent.