370866-03-8

Basic information

• Product Name: 1H-Pyrazolo[3,4-b]pyridine, 5-bromo-4-butoxy-1-[(4-methoxyphenyl)methyl]-
• CAS NO: 370866-03-8
• Molecular Formula: C18H20BrN3O2
• Molecular Weight: 390.28
• Mol File: 370866-03-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazolo[3,4-b]pyridine, 5-bromo-4-butoxy-1-[(4-methoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazolo[3,4-b]pyridine, 5-bromo-4-butoxy-1-[(4-methoxyphenyl)methyl]-(370866-03-8)
• EPA Substance Registry System: 1H-Pyrazolo[3,4-b]pyridine, 5-bromo-4-butoxy-1-[(4-methoxyphenyl)methyl]-(370866-03-8)

Safety Data

• Hazardous Substances Data: 370866-03-8(Hazardous Substances Data)

Upstream product

• 2372-45-4 sodium butanolate 
• 370866-02-7 5-bromo-4-chloro-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridine 
• 71-36-3 butan-1-ol 
• 227617-15-4 4-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester 
• 370865-99-9 4-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid 
• 370866-01-6 5-Bromo-4-hydroxy-1-[(4-methoxyphenyl)methyl]-1H-pyrazolo[3,4-b]pyridine 
• 924909-16-0 1-(4-methoxy-benzyl)-1,7-dihydro-pyrazolo[3,4-b]pyridin-4-one 
• 3528-45-8 1-(4-methoxybenzyl)-1H-pyrazol-5-amine 

Downstream Products

• 370866-05-0 4-butoxy-5-phenylsulfanyl-1H-pyrazolo[3,4-b]pyridine 
• 370866-04-9 4-butoxy-1-(4-methoxy-benzyl)-5-phenylsulfanyl-1H-pyrazolo[3,4-b]pyridine 

Relevant articles and documents

1H-pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases: Highly potent 2,6-difluorophenacyl analogues

Structure-activity studies of 1H-pyrazolo[3,4-b]pyridine 1 have resulted in the discovery of potent CDK1/CDK2 selective inhibitor 21h, BMS-265246 (CDK1/cycB IC50=6 nM, CDK2/cycE IC50=9 nM). The 2,6-difluorophenyl substitution was cri