37107-81-6

Basic information

• Product Name: 5-VINYLURACIL
• Synonyms: 5-VINYL-1H-PYRIMIDINE-2,4-DIONE;5-VINYLURACIL;2,4(1H,3H)-Pyrimidinedione, 5-ethenyl- (9CI);5-Ethenyl-2,4(1H,3H)-pyrimidinedione;NSC 208961;5-Vinyluracil,5-Vinyl-1H-pyrimidine-2,4-dione;5-Ethenyl-;5-Vinylpyrimidine-2,4(1H,3H)-dione
• CAS NO: 37107-81-6
• Molecular Formula: C₆H₆N₂O₂
• Molecular Weight: 138.12
• Product Categories: PYRIMIDINE;Nucleotides and Nucleosides;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals
• Mol File: 37107-81-6.mol
• Article Data: 8

Chemical Properties

• Melting Point: >300 °C (dec.)(lit.)
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /Powder
• Density: 1.332g/cm³
• Refractive Index: 1.606
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated), Water
• PKA: 8.57±0.10(Predicted)
• CAS DataBase Reference: 5-VINYLURACIL(CAS DataBase Reference)
• NIST Chemistry Reference: 5-VINYLURACIL(37107-81-6)
• EPA Substance Registry System: 5-VINYLURACIL(37107-81-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 37107-81-6(Hazardous Substances Data)

Usage

Chemical Properties

Pale Yellow Solid

Uses

A new nucleoside analog active against tumor cells.

InChI:InChI=1/C6H6N2O2/c1-2-4-3-7-6(10)8-5(4)9/h2-3H,1H2,(H2,7,8,9,10)

Upstream product

• 77530-00-8 5-(bromoethynyl)-uracil 
• 108-05-4 vinyl acetate 
• 696-07-1 5-iodouracil 
• 7486-35-3 tri-n-butyl(vinyl)tin 

Downstream Products

• 55520-67-7 5-vinyl-2'-deoxyuridine 
• 69304-49-0 (E)-5-(2-bromovinyl)uracil 
• 131194-29-1 1-<<2-<(tert-butyldimethylsilyl)oxy>ethoxy>methyl>-6-(phenylthio)-5-vinyluracil 
• 69304-48-9 (E)-5-(2-Iodovinyl)-2'-deoxyuridine 
• 73446-77-2 C₂₇H₂₅IN₂O₇ 
• 73456-10-7 E-5-(2-iodovinyl)-3',5'-di-O-p-toluoyl-2'-deoxyuridine 
• 87782-49-8 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-vinyluracil 
• 87782-45-4 1-(3-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-vinyluracil 
• 39541-85-0 5-(1-hydroxyethyl)uracil 
• 137500-15-3 5-vinyl-2,4-dichloropyrimidine 
• 111375-52-1 5-(2-phenylthioethyl)uracil 

Relevant articles and documents

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Inhibition of mycobacterial replication by pyrimidines possessing various C-5 functionalities and related 2′-deoxynucleoside analogues using in vitro and in vivo models

Tuberculosis (TB) has become an increasing problem since the emergence of human immunodeficiency virus and increasing appearance of drug-resistant strains. There is an urgent need to advance our knowledge and discover a new class of agents that are distin

5-Fluorouracil derivatives

Novel compounds comprising 5-fluorouracil or 5-fluorouridine covalently linked to 5-ethynyluracil, 5-ethynyluridine or 5-propynyluracil and pharmaceutical compositions comprising such compounds are disclosed.

Antiviral pyrimidine nucleosides

Pyrimidine 4'-thionucleosides of the formula I STR1 wherein Y is hydroxy or amino, and X is chloro, bromo, iodo, trifluoromethyl, C2-6 alkyl, C2-6 alkenyl, C2-6 haloalkenyl or C2-6 alkynyl and physiologically functional derivatives thereof. These compounds have utility as anti-vital agents.