373362-17-5Relevant articles and documents
Highly efficient sequence-specific DNA interstrand cross-linking by pyrrole/imidazole CPI conjugates
Bando, Toshikazu,Narita, Akihiko,Saito, Isao,Sugiyama, Hiroshi
, p. 3471 - 3485 (2007/10/03)
We have developed a novel type of DNA interstrand cross-linking agent by synthesizing dimers of a pyrrole (Py)/imidazole (Im)-diamide-CPI conjugate, ImPyLDu86 (1), connected using seven different linkers. The tetramethylene linker compound, 7b, efficientl