3736-70-7Relevant articles and documents
The complex role of the triphenylmethyl motif in anticancer compounds
Palchaudhuri, Rahul,Nesterenko, Vitaliy,Hergenrother, Paul J.
supporting information; experimental part, p. 10274 - 10281 (2009/02/04)
Compounds incorporating the triphenylmethyl motif constitute an emerging family of potent anticancer agents. Although several small molecules containing this pharmacophore have now been identified, the mechanism of cell death induction for some of these c
Phosphorylation of Adamantane and its Derivatives in Trifluoroacetic Acid Medium
Shokova,Erokhin,Kovalev
, p. 1624 - 1634 (2007/10/03)
The possibility of dichlorophosphorylation of the carcass compounds of the adamantane series and of aryl(alkyl)carbinols, with phosphorus trichloride in the low-nucleophilicity trifluoroacetic acid medium was first demonstrated. A new preparative method for introducing a POCl2 group into the bridgehead and bridge positions of the adamantane nucleus, as well as into the α position of the side chain was developed. Some intermediate adamantyl cations may undergo isometizations, among them skeleton ones. A mechanism of the phosphorylation was proposed.
