37404-23-2

Basic information

• Product Name: Propanoic acid, 2-(4-iodophenoxy)-2-methyl-
• CAS NO: 37404-23-2
• Molecular Formula: C10H11IO3
• Molecular Weight: 306.1
• Mol File: 37404-23-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-(4-iodophenoxy)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-(4-iodophenoxy)-2-methyl-(37404-23-2)
• EPA Substance Registry System: Propanoic acid, 2-(4-iodophenoxy)-2-methyl-(37404-23-2)

Safety Data

• Hazardous Substances Data: 37404-23-2(Hazardous Substances Data)

Upstream product

• 540-38-5 p-Iodophenol 
• 37404-22-1 ethyl 2-(4-iodophenoxy)-2-methylpropanoate 
• 67-66-3 chloroform 
• 67-64-1 acetone 

Downstream Products

• 17431-97-9 2-(4-nitrophenoxy)-2-methylpropanoic acid 
• 124188-27-8 2-(4-iodo-2-nitrophenoxy)-2-methylpropanoic acid 
• 29941-94-4 2-(4-benzoylphenoxy)-2-methylpropanoic acid 
• 42017-89-0 fenofibric acid 
• 37404-22-1 ethyl 2-(4-iodophenoxy)-2-methylpropanoate 

Relevant articles and documents

Water-based biphasic media for exothermic reactions: Green chemistry strategy for the large scale preparation of clofibric acid and analogues

A water-based biphasic reaction process has been developed for conducting exothermic reactions without organic solvents. This procedure is rapid, simple, and suitable for small scale synthesis as well as larger (multi-molar) scale reactions. The preparation of several hundred grams of clofibric acid and analogues by this eco-friendly and energy-efficient procedure is described. Smaller amounts of these compounds were prepared by the friction-activated 'Grindstone Chemistry' method described previously.

WNT PATHWAY MODULATORS

The invention provides a compound of structure Ar1-Ar2-X-C(R1R2)-C(=O)-N(R3)-Ar3-Ar4 for modulating WNT activity. In this structure, Ar1, Ar2, Ar3 and Ar4 are, independently, optionally substituted aryl or heteroaryl groups; R1 and R3 are, independently, H or optionally substituted alkyl groups; R2 is H or an optionally substituted alkyl group or an alkylene group which, together with the carbon atom to which it is attached and X, forms a non-aromatic ring or an alkylene group which, together with the carbon atom to which it is attached and X and two adjacent atoms of Ar2, forms a non-aromatic ring; X is O, CR4R5, N or NR4, wherein if X is N, it is bonded to R2; R4 is H, optionally substituted alkyl or an alkylene chain, optionally containing a heteroatom and/or a carbonyl group, which, together with the C or N to which it is attached and two adjacent atoms of Ar2, forms a non-aromatic ring; R5 is H, NH2 or an optionally substituted alkyl group.