374064-04-7

Basic information

• Product Name: 1-PYRIDIN-3-YLBUTANE-1,4-DIAMINE
• Synonyms: 1-PYRIDIN-3-YLBUTANE-1,4-DIAMINE;3-(1,4-Diaminobut-1-yl)pyridine
• CAS NO: 374064-04-7
• Molecular Formula: C9H15N3
• Molecular Weight: 165.24
• Mol File: 374064-04-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 318.3 °C at 760 mmHg
• Flash Point: 172.2 °C
• Appearance: /
• Density: 1.055 g/cm³
• Vapor Pressure: 0.000364mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: 1-PYRIDIN-3-YLBUTANE-1,4-DIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PYRIDIN-3-YLBUTANE-1,4-DIAMINE(374064-04-7)
• EPA Substance Registry System: 1-PYRIDIN-3-YLBUTANE-1,4-DIAMINE(374064-04-7)

Safety Data

• Hazard Codes: F,T
• Hazardous Substances Data: 374064-04-7(Hazardous Substances Data)

Usage

Description

1-Pyridin-3-ylbutane-1,4-diamine, also known as PD168393, is a chemical compound that serves as a selective inhibitor of the ErbB receptor tyrosine kinase. This kinase is crucial in cell proliferation and survival, and its overexpression is often associated with cancer cells. PD168393 has garnered attention in research and pharmaceutical development due to its potential applications in various therapeutic areas.

Uses

Used in Pharmaceutical Development:
1-Pyridin-3-ylbutane-1,4-diamine is used as a research compound for developing targeted cancer therapies. Its selectivity for the ErbB receptor tyrosine kinase makes it a promising candidate for inhibiting the growth and signaling of cancer cells, particularly those overexpressing the ErbB family of receptors.
Used in Cancer Treatment:
In the field of oncology, 1-Pyridin-3-ylbutane-1,4-diamine is used as a potential therapeutic agent for treating cancers with ErbB receptor overexpression. Its ability to target and inhibit the ErbB kinase activity suggests its potential in managing tumor growth and progression.
Used in Research:
1-Pyridin-3-ylbutane-1,4-diamine is utilized in research settings to study the role of ErbB receptors in cell proliferation, survival, and the development of cancer. This helps in understanding the underlying mechanisms of cancer and identifying new targets for treatment.
Used in Other Disease Research:
Beyond cancer treatment, 1-Pyridin-3-ylbutane-1,4-diamine is also studied for its potential role in other diseases and conditions related to the ErbB receptors. This includes neurodegenerative disorders and cardiovascular diseases, where the ErbB receptor family may play a significant role in disease progression.

InChI:InChI=1/C9H15N3/c10-5-1-4-9(11)8-3-2-6-12-7-8/h2-3,6-7,9H,1,4-5,10-11H2