374064-06-9

Basic information

• Product Name: 2-(2-PYRIDIN-4-YL-1H-INDOL-3-YL)ETHANAMINE MONOHYDROCHLORIDE
• Synonyms: 2-(2-PYRIDIN-4-YL-1H-INDOL-3-YL)ETHANAMINE MONOHYDROCHLORIDE;2-(2-Pyridin-4-yl-1H-indol-3-yl)ethanamine hydrochloride;2-(2-Pyridin-4-yl-1H-indol-3-yl)ethylamine hydrochloride;2-[2-(pyridin-4-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
• CAS NO: 374064-06-9
• Molecular Formula: C15H16ClN3
• Molecular Weight: 273.76
• Mol File: 374064-06-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 479.8 °C at 760 mmHg
• Flash Point: 275.6 °C
• Appearance: /
• Vapor Pressure: 2.29E-09mmHg at 25°C
• CAS DataBase Reference: 2-(2-PYRIDIN-4-YL-1H-INDOL-3-YL)ETHANAMINE MONOHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-PYRIDIN-4-YL-1H-INDOL-3-YL)ETHANAMINE MONOHYDROCHLORIDE(374064-06-9)
• EPA Substance Registry System: 2-(2-PYRIDIN-4-YL-1H-INDOL-3-YL)ETHANAMINE MONOHYDROCHLORIDE(374064-06-9)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 374064-06-9(Hazardous Substances Data)

Usage

Description

2-(2-PYRIDIN-4-YL-1H-INDOL-3-YL)ETHANAMINE MONOHYDROCHLORIDE, also known as LY411575, is a chemical compound that functions as a gamma-secretase inhibitor. It is recognized for its potent ability to inhibit the production of amyloid-beta, a protein linked to the development of Alzheimer's disease. 2-(2-PYRIDIN-4-YL-1H-INDOL-3-YL)ETHANAMINE MONOHYDROCHLORIDE is utilized in research settings to explore its potential as a therapeutic agent for neurodegenerative conditions.

Uses

Used in Pharmaceutical Research:
2-(2-PYRIDIN-4-YL-1H-INDOL-3-YL)ETHANAMINE MONOHYDROCHLORIDE is used as a research tool for investigating the role of gamma-secretase in the pathogenesis of Alzheimer's disease. Its application is crucial in understanding the mechanisms of amyloid-beta production and the subsequent development of neurodegenerative conditions.
Used in Alzheimer's Disease Treatment:
In the field of neurology, 2-(2-PYRIDIN-4-YL-1H-INDOL-3-YL)ETHANAMINE MONOHYDROCHLORIDE is being explored as a potential therapeutic agent for Alzheimer's disease. It is used to inhibit the activity of gamma-secretase, thereby reducing the production of amyloid-beta peptides, which are implicated in the disease's progression.
Used in Neurodegenerative Disease Research:
Beyond Alzheimer's disease, 2-(2-PYRIDIN-4-YL-1H-INDOL-3-YL)ETHANAMINE MONOHYDROCHLORIDE is also used in the broader field of neurodegenerative research. It serves as a valuable compound for studying the underlying processes of other conditions that may involve similar pathological mechanisms, such as the accumulation of misfolded proteins or the dysregulation of proteolytic pathways.

InChI:InChI=1/C15H15N3.ClH/c16-8-5-13-12-3-1-2-4-14(12)18-15(13)11-6-9-17-10-7-11;/h1-4,6-7,9-10,18H,5,8,16H2;1H