37454-52-7

Basic information

• Product Name: 5-morpholinopyrimidine-2,4(1H,3H)-dione
• Synonyms: 5-morpholinopyrimidine-2,4(1H,3H)-dione;5-Morpholin-4-yl-1H-pyrimidine-2,4-dione
• CAS NO: 37454-52-7
• Molecular Formula: C8H11N3O3
• Molecular Weight: 197.19124
• Mol File: 37454-52-7.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-morpholinopyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-morpholinopyrimidine-2,4(1H,3H)-dione(37454-52-7)
• EPA Substance Registry System: 5-morpholinopyrimidine-2,4(1H,3H)-dione(37454-52-7)

Safety Data

• Hazardous Substances Data: 37454-52-7(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 51-20-7 5-bromouracil 
• 2435-76-9 5-diazouracil 
• 132785-87-6 5-Diazo-6-morpholin-4-yl-dihydro-pyrimidine-2,4-dione 

Downstream Products

• 280582-23-2 4-(2,4-dichloropyrimidin-5-yl)morpholine 

Relevant articles and documents

Novel 4-substituent-N-(1-substituent-1H-pyrazol-4-yl)-5-morpholinopyrimidin-2-amine derivatives and use thereof

A novel 4 -substituted - N N - (1-substituted - 111H-pyra -4 - yl) -5 - morpholinopyrimidine -2 - amine derivative compound or a pharmaceutically acceptable salt thereof. A pharmaceutical composition for preventing or treating JAK3-related diseases and a method for preventing or treating JAK3-related diseases using the same as an active ingredient are provided.

ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS

The present invention concerns, in a first aspect, compounds of Formula I as defined herein, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing such compounds. The present invention also relates to compounds of Formula I

Synthesis of substituted uracils by the reactions of halouracils with selenium, sulfur, oxygen and nitrogen nucleophiles under focused microwave irradiation

Under microwave irradiation, the nucleophilic substitution reactions of halouracils with selenium, sulfur, oxygen and nitrogen nucleophiles was complete within several minutes with yields up to 99%. The method using microwave irradiation is superior to th