374726-62-2

Basic information

• Product Name: Mandipropamid
• Synonyms: Mandipropamid;noa 446510;2-(4-Chlorophenyl)-N-[2-[3-methoxy-4-(prop-2-ynyloxy)phenyl]ethyl]-2-(prop-2-ynyloxy)acetamide;2-(4-Chlorophenyl)-N-[3-methoxy-4-(2-propynyloxy)phenethyl]-2-(2-propynyloxy)acetamide;Mandipropamid [iso];2-(4-chlorophenyl)-N-(2-Methoxy-4-(prop-2-yn-1-yloxy)phenethyl)-2-(prop-2-yn-1-yloxy)acetaMide;Mandipropamid Standard;Mandipropamid Solution, 1000ppm
• CAS NO: 374726-62-2
• Molecular Formula: C₂₃H₂₂ClNO₄
• Molecular Weight: 411.88
• Mol File: 374726-62-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 96-97 °C
• Boiling Point: 608.6 °C at 760 mmHg
• Flash Point: 321.8 °C
• Appearance: /
• Density: 1.214g/cm³
• Vapor Pressure: 9.38E-15mmHg at 25°C
• Refractive Index: 1.574
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Dichloromethane (Slightly)
• PKA: 13.90±0.46(Predicted)
• CAS DataBase Reference: Mandipropamid(CAS DataBase Reference)
• NIST Chemistry Reference: Mandipropamid(374726-62-2)
• EPA Substance Registry System: Mandipropamid(374726-62-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 374726-62-2(Hazardous Substances Data)

Usage

Uses

Mandipropamid is a fungicide. It can be used on many fruit and vegetable crops, including potatoes, tomatoes, salad leaves and grapes. Manufactured by Syngenta.

InChI:InChI=1/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)

Upstream product

• 624-65-7 2-propynyl chloride 
• 282720-26-7 2-(4-chlorophenyl)-2-hydroxy-N-[2-(3-methoxy-4-(prop-2-ynyloxy)phenyl)ethyl]acetamide 
• 106-96-7 propargyl bromide 

Relevant articles and documents

Multicomponent reactions in fungicide research: The discovery of mandipropamid

Isocyanide-based multicomponent reactions of the Ugi- and Passerini-type have been valuable tools for the rapid exploration of the novel fungicidal compound classes of phenylglycinamides and mandelamides. Mandipropamid (6), which was discovered during this derivatisation, displays excellent activity against the economically important phytopathogens Phytophthora infestans (potato and tomato late blight) and Plasmopara viticola (grape downy mildew).

Phenyl-propargylether derivatives

The invention relates to phenyl-propargylether derivatives of the general formula I including the optical isomers thereof and mixtures of such isomers, wherein R1is hydrogen, alkyl, cycloalkyl or optionally substituted aryl, R2and R3are each independently hydrogen or alkyl, R4is alkyl, alkenyl or alkynyl, R5, R6, R7, and R8are each independently hydrogen or alkyl, R9is hydrogen, optionally substituted alkyl, optionally substituted alkenyl or optionally substituted alkynyl, R10is optionally substituted aryl or optionally substituted heteroaryl, and Z is halogen, optionally substituted aryloxy, optionally substituted alkoxy, optionally substituted alkenyloxy, optionally substituted alkynyloxy, optionally substituted arylthio, optionally substituted alkylthio, optionally substituted alkenylthio; optionally substituted alkynylthio, optionally substituted alkylsulfinyl, optionally substituted alkenylsulfinyl, optionally substituted alkynylsulfinyl, optionally substituted alkylsulfonyl, optionally substituted alkenylsulfonyl or optionally substituted alkynylsulfonyl. These compounds possess useful plant protecting properties and may advantageously be employed in agricultural practice for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi.