375369-29-2 Usage
Description
2,4,5-Trifluoromandelic acid is a chemical compound with the molecular formula C9H5F3O3. It is a derivative of mandelic acid, which is a type of aromatic alpha hydroxy acid. 2,4,5-TRIFLUOROMANDELIC ACID is characterized by the presence of three fluorine atoms at the 2nd, 4th, and 5th positions, which impart unique chemical properties to the molecule.
Uses
Used in Chemical Synthesis:
2,4,5-Trifluoromandelic acid is used as a building block for the synthesis of other organic compounds. Its unique structure and reactivity make it a valuable intermediate in the production of various chemical products.
Used in Pharmaceutical Industry:
2,4,5-Trifluoromandelic acid is used as a chiral resolving agent in chromatographic separation processes. This application is crucial for the purification and isolation of enantiomers, which are essential in the development of single-enantiomer drugs to improve efficacy and reduce side effects.
Used in Drug Development:
Due to its unique chemical properties, 2,4,5-Trifluoromandelic acid has potential applications in the development of new drugs and pharmaceuticals. Its ability to interact with biological targets and influence biochemical pathways makes it a promising candidate for the creation of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 375369-29-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,5,3,6 and 9 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 375369-29:
(8*3)+(7*7)+(6*5)+(5*3)+(4*6)+(3*9)+(2*2)+(1*9)=182
182 % 10 = 2
So 375369-29-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H5F3O3/c9-4-2-6(11)5(10)1-3(4)7(12)8(13)14/h1-2,7,12H,(H,13,14)
375369-29-2Relevant articles and documents
EFFICIENT PROCESS FOR THE PREPARATION OF SITAGLIPTIN THROUGH A VERY EFFECTIVE PREPARATION OF THE INTERMEDIATE 2,4,5-TRIFLUOROPHENYLACETIC ACID
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Paragraph 00159; 00160, (2019/01/21)
Object of the present invention is an efficient process for the preparation of the active pharmaceutical ingredient Sitagliptine and the 2,4,5-trifluorophenylacetic acid (TFAA) and salt thereof, which is a key intermediate for the synthesis of Sitagliptine.
