375857-65-1 Usage
Chemical Properties
White to off-white solid
Check Digit Verification of cas no
The CAS Registry Mumber 375857-65-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,5,8,5 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 375857-65:
(8*3)+(7*7)+(6*5)+(5*8)+(4*5)+(3*7)+(2*6)+(1*5)=201
201 % 10 = 1
So 375857-65-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H3BrF3N3/c8-5-3-12-6-13-4(7(9,10)11)1-2-14(5)6/h1-3H
375857-65-1Relevant articles and documents
The expedient synthesis of 4,2′-difluoro-5′-(7- trifluoromethylimidazo[1,2-a]pyrimidin-3-yl)biphenyl-2-carbonitrile, a GABA α2/3 agonist
Cameron, Mark,Foster, Bruce S.,Lynch, Joseph E.,Shi, Yao-Jun,Dolling, Ulf-H.
, p. 398 - 402 (2012/12/22)
An expedient regioselective synthesis of a GABA α2/3 agonist 1 is described. The key step is an efficient regioselective palladium-catalyzed coupling of 7-trifluoromethylimidazo[1,2-a]pyrimidine (5) to 5′-chloro-4,2′-difluorobiphenyl-2-carbonitrile (15).
