37595-72-5

Basic information

• Product Name: Methanesulfonamide, 1,1,1-trifluoro-N-(3-methylphenyl)-
• Synonyms: Methanesulfonamide, 1,1,1-trifluoro-N-(3-methylphenyl)-
• CAS NO: 37595-72-5
• Molecular Formula: C₈H₈F₃NO₂S
• Molecular Weight: 0
• Mol File: 37595-72-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methanesulfonamide, 1,1,1-trifluoro-N-(3-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonamide, 1,1,1-trifluoro-N-(3-methylphenyl)-(37595-72-5)
• EPA Substance Registry System: Methanesulfonamide, 1,1,1-trifluoro-N-(3-methylphenyl)-(37595-72-5)

Safety Data

• Hazardous Substances Data: 37595-72-5(Hazardous Substances Data)

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 108-44-1 1-amino-3-methylbenzene 
• 421-83-0 trifluoromethane sulfonyl chloride 
• 3855-45-6 triflic azide 
• 108-88-3 toluene 

Downstream Products

• 643-93-6 3-methylbiphenyl 
• 1309965-19-2 N-(4-hydroxy-3-methylphenyl)-1,1,1-trifluoromethanesulfonamide 

Relevant articles and documents

NHC-Nickel Catalyzed C-N Bond Cleavage of Mono-protected Anilines for C-C Cross-Coupling

A Ni-catalyzed aryl C-N bond cleavage of mono-protected anilines, N-arylsulfonamides, has been developed. A new N-heterocyclic carbene derived from benzoimidazole shows high reactivity for the C-N cleavage/C-C cross-coupling reaction. The ortho-directing group is not required to break the C-N bond of sulfonyl-protected anilines, which are not limited to π-extended anilines. The mechanistic studies have revealed that a sulfamidomagnesium salt is the key coupling intermediate.