37629-77-9

Basic information

• Product Name: (Z)-2-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)acrylonitrile
• Synonyms: (Z)-2-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)acrylonitrile
• CAS NO: 37629-77-9
• Molecular Weight: 295.338
• Mol File: 37629-77-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (Z)-2-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)acrylonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)acrylonitrile(37629-77-9)
• EPA Substance Registry System: (Z)-2-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)acrylonitrile(37629-77-9)

Safety Data

• Hazardous Substances Data: 37629-77-9(Hazardous Substances Data)

Upstream product

• 2460-33-5 3,4-dimethoxyphenylpyruvic acid 
• 93-17-4 3,4-dimethoxyphenylacetonitrile 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 114651-98-8 (E)-2-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)acrylaldehyde 
• 1346463-56-6 4-(3,4-dimethoxyphenyl)-5-(4-methoxyphenyl)penta-(2E,4Z)-dienoyl azide 
• 1346463-43-1 4-(3,4-dimethoxyphenyl)-5-(4-methoxyphenyl)penta-(2E,4Z)-dienoic acid 
• 1346463-84-0 (Z)-2-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)acrylaldehyde 
• 74272-62-1 10-cyano-2,3,6-trimethoxyphenanthrene 
• 1150647-81-6 (E)-α-(3,4-dimethoxyphenyl)-4-methoxycinnamonitrile 
• 102473-35-8 3-(3,4-dimethoxy-phenyl)-4-(4-methoxy-phenyl)-3-methyl-hexan-2-one 

Relevant articles and documents

Cyano Group Removal from Cyano-Promoted Aza-Diels-Alder Adducts: Synthesis and Structure-Activity Relationship of Phenanthroindolizidines and Phenanthroquinolizidines

Phenanthroindolizidines and phenanthroquinolizidines were concisely synthesized by the reductive decyanization of cyano-promoted intramolecular aza-Diels-Alder cycloadducts followed by aryl-aryl coupling. Cyano groups were removed from α-aminoacrylonitriles via treatment with sodium borohydride in 2-propanol in almost quantitative yields; a possible mechanism was proposed and examined using D-labeling experiments. A systematic study of the effects of the phenanthrene substitution pattern on the anticancer activity against three human cancer cell lines was discussed. (Chemical Equation Presented).

Synthesis of phenanthro[9,10-b]indolizidin-9-ones, phenanthro[9,10-b] quinolizidin-9-one, and related benzolactams by Pd(OAc)2-catalyzed direct aromatic carbonylation

Phenanthro[9,10-b]indolizidin-9-ones, phenanthro[9,10-b]-quinolizidin-9- one, and related benzolactams were synthesized by benzolactam ring formation using Pd(OAc)2-catalyzed direct aromatic carbonylation. This also constitutes a formal synthesis of the representative phenanthroindolizidine and -quinolizidine alkaloids (±)-tylophorine, (±)-antofine, and (±)-cryptopleurine. Wiley-VCH Verlag GmbH & Co. KGaA, 2009.