37632-19-2 Usage
Description
(4-methoxyphenyl)phosphonothioic dichloride, also known as 4-Methoxyphenyl phosphorothioyl dichloride, is a chlorinated organophosphorus compound with the molecular formula C7H8Cl2O2PS. It is a derivative of phosphonothioic acid and is commonly used as an intermediate in the synthesis of pharmaceuticals and agricultural chemicals.
Uses
Used in Pharmaceutical Industry:
(4-methoxyphenyl)phosphonothioic dichloride is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs.
Used in Agricultural Chemical Industry:
(4-methoxyphenyl)phosphonothioic dichloride is used as a chemical intermediate in the production of agricultural chemicals. It has potential applications as a pesticide, insecticide, and fungicide, making it valuable in crop protection and management.
Safety Precautions:
Due to its toxic and corrosive nature, (4-methoxyphenyl)phosphonothioic dichloride should be handled with care and proper safety measures should be taken when working with this compound. This includes wearing appropriate personal protective equipment, working in a well-ventilated area, and following established safety protocols.
Check Digit Verification of cas no
The CAS Registry Mumber 37632-19-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,6,3 and 2 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 37632-19:
(7*3)+(6*7)+(5*6)+(4*3)+(3*2)+(2*1)+(1*9)=122
122 % 10 = 2
So 37632-19-2 is a valid CAS Registry Number.
37632-19-2Relevant articles and documents
Investigating the generation of hydrogen sulfide from the phosphonamidodithioate slow-release donor GYY4137
Alexander, Benjamin E.,Coles, Simon J.,Fox, Bridget C.,Khan, Tahmina F.,Maliszewski, Joseph,Perry, Alexis,Pitak, Mateusz B.,Whiteman, Matthew,Wood, Mark E.
supporting information, p. 1649 - 1655 (2015/09/21)
A combination of NMR spectroscopy, mass spectrometry and chemical synthesis was used to elucidate the two-step hydrolytic decomposition pathway of the slow-release hydrogen sulfide (H2S) donor GYY4137 and the key decomposition product was also prepared by an independent synthetic route. The (dichloromethane-free) sodium salt of the phosphonamidodithioate GYY4137 was also produced as a pharmaceutically more acceptable salt. In contrast with GYY4137 and its sodium salt, the decomposition product did not generate H2S or exert cytoprotective or anti-inflammatory effects in oxidatively stressed human Jurkat T-cells and LPS-treated murine RAW264.7 macrophages. The decomposition product represents a useful control compound for determining the biological and pharmacological effects of H2S generated from GYY4137.
