37642-65-2

Basic information

• Product Name: ARG-PRO-HYP-GLY-PHE-SER-PRO-PHE-ARG
• Synonyms: ARG-PRO-HYP-GLY-PHE-SER-PRO-PHE-ARG;ARG-PRO-HYP-GLY-PHE-SER-PRO-PHE-ARG 2ACOH 3H2O;BRADYKININ [HYP3];H-ARG-PRO-HYP-GLY-PHE-SER-PRO-PHE-ARG-OH;[HYP3]-BRADYKININ;[HYP3]-BRADYKININ (HUMAN);[HYP3]-BRADYKININ (HUMAN) 2ACOH 3H2O;bradykinin, hydroxy-Pro(3)-
• CAS NO: 37642-65-2
• Molecular Formula: C50H73N15O12
• Molecular Weight: 1076.21
• Product Categories: Peptide;Bradykinins;Peptides and Proteins;Peptides for Cell Biology
• Mol File: 37642-65-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.52g/cm³
• Refractive Index: 1.699
• Storage Temp.: −20°C
• CAS DataBase Reference: ARG-PRO-HYP-GLY-PHE-SER-PRO-PHE-ARG(CAS DataBase Reference)
• NIST Chemistry Reference: ARG-PRO-HYP-GLY-PHE-SER-PRO-PHE-ARG(37642-65-2)
• EPA Substance Registry System: ARG-PRO-HYP-GLY-PHE-SER-PRO-PHE-ARG(37642-65-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 37642-65-2(Hazardous Substances Data)

Usage

Description

ARG-PRO-HYP-GLY-PHE-SER-PRO-PHE-ARG, also known as an analogue of bradykinin, is an oligopeptide that differs from the original bradykinin by having hydroxyproline (HYP) as the third amino acid instead of proline (PRO). This modification may result in altered biological activities and properties, making it a potential candidate for various applications in different industries.

Uses

Used in Pharmaceutical Industry:
ARG-PRO-HYP-GLY-PHE-SER-PRO-PHE-ARG is used as a pharmaceutical agent for its potential therapeutic effects. As an analogue of bradykinin, it may exhibit similar biological activities, such as vasodilation, pain transmission, and inflammation regulation. The substitution of hydroxyproline for proline could lead to enhanced stability or altered interactions with receptors, making it a valuable compound for drug development.
Used in Research and Development:
In the field of research and development, ARG-PRO-HYP-GLY-PHE-SER-PRO-PHE-ARG serves as a valuable tool for studying the structure-function relationships of bradykinin and its analogues. This knowledge can be applied to design new drugs with improved pharmacological properties or to better understand the underlying mechanisms of bradykinin's actions.
Used in Cosmetics Industry:
The potential anti-inflammatory and vasodilatory properties of ARG-PRO-HYP-GLY-PHE-SER-PRO-PHE-ARG may also find applications in the cosmetics industry. It could be used as an active ingredient in skincare products aimed at reducing inflammation, improving blood circulation, and providing a soothing effect on the skin.
Used in Diagnostics:
Due to its structural similarity to bradykinin, ARG-PRO-HYP-GLY-PHE-SER-PRO-PHE-ARG may be utilized in the development of diagnostic tools and assays to detect and measure bradykinin levels in biological samples. This could be particularly useful in studying the role of bradykinin in various physiological and pathological processes.

InChI:InChI=1/C50H73N15O12/c51-32(15-7-19-56-49(52)53)45(73)64-22-10-18-38(64)47(75)65-27-31(67)25-39(65)43(71)58-26-40(68)59-34(23-29-11-3-1-4-12-29)41(69)62-36(28-66)46(74)63-21-9-17-37(63)44(72)61-35(24-30-13-5-2-6-14-30)42(70)60-33(48(76)77)16-8-20-57-50(54)55/h1-6,11-14,31-39,66-67H,7-10,15-28,51H2,(H,58,71)(H,59,68)(H,60,70)(H,61,72)(H,62,69)(H,76,77)(H4,52,53,56)(H4,54,55,57)/t31-,32+,33+,34+,35+,36+,37+,38+,39+/m1/s1