376592-57-3 Usage
General Description
"[1,1'-Biphenyl]-3-carboxylic acid, 5'-chloro-2'-hydroxy-" is a type of organochlorine compound, specifically a derivative of biphenyl. It gains its name from the changes in the basic biphenyl structure, which include the addition of a carboxylic acid (COOH) on the third carbon and a hydroxy (-OH) and chloro (-Cl) groups at the second and fifth carbons of the other ring, respectively. The ‘chloro’ prefix indicates that this compound includes a chlorine atom, and the ‘hydroxy’ term represents the presence of a hydroxyl group. It can be used for various purposes, including as an intermediate in some organic reactions. Precise information about its specific uses, hazards, and handling precautions should be taken from a detailed reference or material safety data sheet.
Check Digit Verification of cas no
The CAS Registry Mumber 376592-57-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,6,5,9 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 376592-57:
(8*3)+(7*7)+(6*6)+(5*5)+(4*9)+(3*2)+(2*5)+(1*7)=193
193 % 10 = 3
So 376592-57-3 is a valid CAS Registry Number.
376592-57-3Relevant articles and documents
PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES FOR THE SYNTHESIS OF ELTROMBOPAG OR SALT THEREOF
-
Paragraph 00133, (2021/01/23)
Object of the present invention is an improved process for the preparation of key intermediates for the synthesis of Eltrombopag, passing through/using intermediate 5'-Chloro-2'-hydroxy[1,1'-biphenyl]-3-carboxylic acid alkaline metal salt of formula: wherein A is an alkaline metal.
Thrombopoietin mimetics
-
Page 22, (2008/06/13)
Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
