37719-98-5

Basic information

• Product Name: Angelicone
• Synonyms: Angelicone;5,7-Dimethoxy-8-(3-methyl-1-oxo-2-butenyl)-2H-1-benzopyran-2-one;5,7-Dimethoxy-8-(3-methyl-1-oxo-2-butenyl)coumarin;Glabralactone
• CAS NO: 37719-98-5
• Molecular Formula: C16H16O5
• Molecular Weight: 288.29524
• Mol File: 37719-98-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Angelicone(CAS DataBase Reference)
• NIST Chemistry Reference: Angelicone(37719-98-5)
• EPA Substance Registry System: Angelicone(37719-98-5)

Safety Data

• Hazardous Substances Data: 37719-98-5(Hazardous Substances Data)

Upstream product

• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 487-06-9 Limettin 
• 37719-97-4 5-hydroxy-7-methoxy-8-seneciylcoumarin 
• 77-78-1 dimethyl sulfate 
• 75239-74-6 8-(3-hydroxyisovaleroyl)-5,7-dimethoxycoumarin 

Downstream Products

• 142878-03-3 toddacoumaquinone 

Relevant articles and documents

Synthesis of toddacoumaquinone, a coumarin-naphthoquinone dimer, and its antiviral activities

Toddacoumaquinone (1), a coumarin-naphthoquinone dimer, was synthesized through Diels-Alder reaction between 8-(1-acetoxy-3-methyl-1,3-butadienyl)-5,7-dimethoxycoumarin (15) and 2-methoxy-1,4-benzoquinone (5). The activities of 1 against several viruses were examined. A weak activity (EC50 = 10 μg/ml) was observed against HSV-1 and HSV-2, but no activity was seen against HIV-1.

Claisen rearrangements. V. Synthesis of the coumarins, dentatin (poncitrin) and glabralactone (angelicone)

-