37827-83-1

Basic information

• Product Name: 2-Naphthalenecarbonyl fluoride (9CI)
• Synonyms: 2-Naphthalenecarbonyl fluoride (9CI)
• CAS NO: 37827-83-1
• Molecular Formula: C₁₁H₇FO
• Molecular Weight: 174.1710832
• Product Categories: ACIDHALIDE
• Mol File: 37827-83-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 283.0±9.0 °C(Predicted)
• Appearance: /
• Density: 1.209±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-Naphthalenecarbonyl fluoride (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Naphthalenecarbonyl fluoride (9CI)(37827-83-1)
• EPA Substance Registry System: 2-Naphthalenecarbonyl fluoride (9CI)(37827-83-1)

Safety Data

• Hazardous Substances Data: 37827-83-1(Hazardous Substances Data)

Upstream product

• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 93-09-4 naphthalene-2-carboxylate 

Downstream Products

• 52258-16-9 4-methylphenyl 2-naphthyl sulfide 
• 613-46-7 2-naphthalenecarbonitrile 
• 23975-17-9 2-phenylethynyl-naphthalene 
• 4842-47-1 1‐(2‐naphthyl)‐3‐phenylpropan‐1‐one 
• 945-77-7 β-naphthyltrimethylstannane 
• 91-20-3 naphthalene 
• 1126479-91-1 triethyl(naphthalen-2-yl)silane 
• 612-78-2 2,2'-binaphthalene 
• 3710-23-4 2-isopropenylnaphthalene 
• 972-11-2 tributyl(naphthalene-2-yl)stannane 

Relevant articles and documents

Direct Synthesis of Tri-/Difluoromethyl Ketones from Carboxylic Acids by Cross-Coupling with Acyloxyphosphonium Ions

A simple and straightforward approach to the synthesis of trifluoromethyl and difluoromethyl ketones from widely available carboxylic acids is disclosed. The transformation utilizes an acyloxyphosphonium ion as the active electrophile, conveniently generated in situ from the carboxylic acid substrate by using commodity chemicals. The utility of the reaction system is exemplified by its chemoselectivity, with tolerance to a variety of important functional groups. The late-stage functionalization of carboxylic acid active pharmaceutical ingredients and pharmaceutically relevant compounds is also discussed.