37839-01-3

Basic information

• Product Name: Aliphatics
• Synonyms: Aliphatics;methyl hydrazinecarbohydrazonothioate hydroiodide;Methyl hydrazine-1-carbohydrazono thioate hydroiod
• CAS NO: 37839-01-3
• Molecular Formula: C₂H₉N₄S*I
• Molecular Weight: 0
• Product Categories: Aliphatics
• Mol File: 37839-01-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 145 °C (decomp)
• Boiling Point: 259.2°C at 760 mmHg
• Flash Point: 110.6°C
• Appearance: /
• Vapor Pressure: 0.0131mmHg at 25°C
• CAS DataBase Reference: Aliphatics(CAS DataBase Reference)
• NIST Chemistry Reference: Aliphatics(37839-01-3)
• EPA Substance Registry System: Aliphatics(37839-01-3)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 37839-01-3(Hazardous Substances Data)

Usage

General Description

Aliphatics are a class of organic compounds that are characterized by straight or branched carbon chains. These compounds can be saturated, meaning they contain only single bonds between carbon atoms, or unsaturated, containing double or triple bonds. Aliphatics include a wide range of important chemicals such as alkanes, alkenes, and alkynes which are used in various industrial processes as solvents, fuels, and as building blocks for the synthesis of other chemicals. They are also found in natural sources such as crude oil, natural gas, and plant oils. Due to their versatility and abundance, aliphatics play a significant role in the chemical industry and contribute to numerous everyday products and materials.

InChI:InChI=1/C2H8N4S.HI/c1-7-2(5-3)6-4;/h3-4H2,1H3,(H,5,6);1H

Upstream product

• 2231-57-4 Thiocarbohydrazide 
• 74-88-4 methyl iodide 

Relevant articles and documents

Divergent Synthesis of Monosubstituted and Unsymmetrical 3,6-Disubstituted Tetrazines from Carboxylic Ester Precursors

Since tetrazines are important tools to the field of bioorthogonal chemistry, there is a need for new approaches to synthesize unsymmetrical and 3-monosubstituted tetrazines. Described here is a general, one-pot method for converting (3-methyloxetan-3-yl)methyl carboxylic esters into 3-thiomethyltetrazines. These versatile intermediates were applied to the synthesis of unsymmetrical tetrazines through Pd-catalyzed cross-coupling and in the first catalytic thioether reduction to access monosubstituted tetrazines. This method enables the development of new tetrazine compounds possessing a favorable combination of kinetics, small size, and hydrophilicity. It was applied to a broad range of aliphatic and aromatic ester precursors and to the synthesis of heterocycles including BODIPY fluorophores and biotin. In addition, a series of tetrazine probes for monoacylglycerol lipase (MAGL) were synthesized and the most reactive one was applied to the labeling of endogenous MAGL in live cells.