37875-78-8Relevant articles and documents
Lewis acid-catalyzed sequential transformations: Straightforward preparation of functional dihydropyridines
Vohra, Ramandeep Kaur,Bruneau, Christian,Renaud, Jean-Luc
, p. 2571 - 2574 (2006)
Lewis acids catalyze the addition of β-enaminoacrylates or β-enaminones to α,β-unsaturated aldehydes leading to substituted dihydropyridines in high yields under mild reaction conditions.
A mild route for one pot synthesis of 5,6-unsubstituted 1,4-dihydropyridines catalyzed by sulphated mixed metal oxides
Kahandal, Sandeep S.,Kale, Sandip R.,Gawande, Manoj B.,Jayaram, Radha V.
, p. 672 - 680 (2014/03/21)
Synthesis of 1,4-dihydropyridines via a four component one pot reaction starting from α,β-unsaturated aldehyde, β-keto ester, amine and alcohol, catalysed by SO42-/CexZr 1-xO2 is explored. The method has several advantages such as reusability of catalyst, avoidance of a multistep procedure and readily available starting materials. The protocol gives high to moderate yields for structurally diverse amines, β-keto esters and α,β-unsaturated aldehydes. SO42-/CexZr1-xO 2 (x = 0.02-0.15 mol%) catalysts were prepared and characterized by various analytical techniques such as XRD, FT-IR, TGA-DSC, SEM-EDAX and the total acidity.
Silica-supported perchloric acid catalyzed one-pot synthesis of 1,4-dihydropyridines
Ramesh, Dasari,Rajaram, Singanaboina,Narasimhulu, Manchala,Reddy, Thummalpally Srikanth,Mahesh, Kondempudi Chinni,Manasa, Gajji,Venkateswarlu, Yenamandra
experimental part, p. 2471 - 2475 (2012/02/03)
An environmentally friendly and highly efficient procedure for the preparation of 1,4-dihydropyridines by the reaction between α,β- unsaturated aldehydes, aromatic amines and β-keto esters in the presence of silica supported perchloric acid is described.
Sulfonic acid functionalized silica: An efficient heterogeneous catalyst for a three-component synthesis of 1,4-dihydropyridines under solvent-free conditions
Das, Biswanath,Suneel, Kanaparthy,Venkateswarlu, Katta,Ravikanth, Bommena
, p. 366 - 368 (2008/12/23)
Sulfonic acid functionalized silica catalyzed the three-component reaction of aromatic amines, α,β -unsaturated aldehydes and β-keto esters forming the corresponding 1,4-dihydropyridines in short reaction times and in high yields.
