3790-90-7

Basic information

• Product Name: 1,3-Benzenediol, 5-(1,1-dimethylethyl)-
• CAS NO: 3790-90-7
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• Mol File: 3790-90-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3-Benzenediol, 5-(1,1-dimethylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzenediol, 5-(1,1-dimethylethyl)-(3790-90-7)
• EPA Substance Registry System: 1,3-Benzenediol, 5-(1,1-dimethylethyl)-(3790-90-7)

Safety Data

• Hazardous Substances Data: 3790-90-7(Hazardous Substances Data)

Usage

Chemical structure

1,3-Benzenediol, 5-(1,1-dimethylethyl)-

Type of compound

Derivative of resorcinol

Application

Skincare and cosmetic products

Purpose

Skin lightening and anti-aging properties

Mechanism of action

Inhibits tyrosinase enzyme, responsible for melanin production

Result

Decreased pigmentation and more even skin tone

Additional property

Antioxidant

Function of antioxidant property

Protects skin from damage caused by free radicals and environmental stressors

Industry

Popular ingredient in the skincare industry

Upstream product

• 500878-03-5 3-tert-butyl-5-nitro-aniline 
• 3790-99-6 3-Nitro-5-tert.butyl-phenol 
• 22385-63-3 1-tert-butyl-3,5-dinitro-benzene 
• 80754-02-5 4-tert-butyl-2,6-dimethoxyphenyl diethyl phosphate 
• 6766-84-3 4-(tert-butyl)-2,6-dimethoxyphenol 
• 91-10-1 1,3-dimethoxy-2-hydroxy-benzene 
• 143029-45-2 2-methyl-2-(3,5-dimethoxyphenyl)propane 
• 3791-00-2 3-Amino-5-tert.-butyl-phenol 

Downstream Products

• 3790-91-8 2-tert-butyl-6-hydroxy-p-benzoquinone 
• 29100-97-8 2,4,4-Trimethyl-3-oxo-pentanoic acid 3-tert-butyl-5-hydroxy-phenyl ester 
• 29100-96-7 2,4,4-Trimethyl-3-oxo-pentanoic acid 3-tert-butyl-5-(2,4,4-trimethyl-3-oxo-pentanoyloxy)-phenyl ester 
• 3790-95-2 6-Hydroxy-2-tert.butyl-3-<2,5-dioxo-3-tert.butyl-cyclopent-3-en-yl>-1,4-benzochinon 
• 1260029-59-1 4,6,16,18-tetraaza-11-tert-butyl-5,17-diphenyl-2,8,14,20,26-pentaoxacalix[5]arene 

Relevant articles and documents

3-(1',1'-Dimethylbutyl)-1-deoxy-Δ8-THC and related compounds: Synthesis of selective ligands for the CB2 receptor

The synthesis and pharmacology of 15 1-deoxy-Δ8-THC analogues, several of which have high affinity for the CB2 receptor, are described. The deoxy cannabinoids include 1-deoxy-11-hydroxy-Δ8-THC (5), 1-deoxy-Δ8-THC (6), 1-deoxy-3-butyl-Δ8-THC (7), 1-deoxy-3-hexyl-Δ8-THC (8) and a series of 3-(1',1'-dimethylalkyl)-1-deoxy-Δ8-THC analogues (2, n=0-4, 6, 7, where n=the number of carbon atoms in the side chain-2). Three derivatives (17-19Scheme 3(a) (C6H5)3PCH3+ Br-, n-BuLi/THF, 65°C; (b) LiAlH4/THF, 25°C; (c) KBH(sec-Bu)3/THF, -78 to 25°C then H2O2/NaOH.) of deoxynabilone (16) were also prepared. The affinities of each compound for the CB1 and CB2 receptors were determined employing previously described procedures. Five of the 3-(1',1'-dimethylalkyl)-1-deoxy-Δ8-THC analogues (2, n=1-5) have high affinity (K(i)=2 receptor. Four of them (2, n=1-4) also have little affinity for the CB1 receptor (K(i)=>295nM). 3-(1',1'-Dimethylbutyl)-1-deoxy-Δ8-THC (2, n=2) has very high affinity for the CB2 receptor (K(i)=3.4±1.0nM) and little affinity for the CB1 receptor (K(i)=677±132nM). Copyright (C) 1999 Elsevier Science Ltd.