3797-94-2

Basic information

• Product Name: 2,6-DICHLOROBENZANILIDE
• Synonyms: 2,6-DICHLOROBENZANILIDE
• CAS NO: 3797-94-2
• Molecular Formula: C₁₃H₉Cl₂NO
• Molecular Weight: 266.12266
• Mol File: 3797-94-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: 178 °C
• Boiling Point: 326.9°C at 760 mmHg
• Flash Point: 151.5°C
• Appearance: /
• Density: 1.384g/cm³
• Vapor Pressure: 0.000209mmHg at 25°C
• Refractive Index: 1.656
• Storage Temp.: 2-8°C
• PKA: 12.08±0.70(Predicted)
• CAS DataBase Reference: 2,6-DICHLOROBENZANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DICHLOROBENZANILIDE(3797-94-2)
• EPA Substance Registry System: 2,6-DICHLOROBENZANILIDE(3797-94-2)

Safety Data

• Hazardous Substances Data: 3797-94-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H9Cl2NO/c14-10-7-4-8-11(15)12(10)13(17)16-9-5-2-1-3-6-9/h1-8H,(H,16,17)

Upstream product

• 103-71-9 phenyl isocyanate 
• 541-73-1 1,3-Dichlorobenzene 
• 1194-65-6 2,6-dichloro-benzonitrile 
• 114-83-0 1-acetyl-2-phenylhydrazine 
• 83-38-5 2,6-dichlorobenzaldehyde 
• 98-95-3 nitrobenzene 
• 77331-22-7 C₁₃H₁₁Cl₂N₂O₇P 
• 87-62-7 2,6-dimethylaniline 
• 62-53-3 aniline 
• 4659-45-4 2,6-Dichlorobenzoyl chloride 

Downstream Products

• 6064-02-4 (2,6-Dichloro-benzoyl)-phenyl-carbamic acid isopropyl ester 
• 113055-87-1 2,6-Dichlor-N-phenylbenzimidchlorid 
• 113035-33-9 Nα-(tert-Butoxycarbonyl)-N-(2,6-dichlorbenzoyl)-N-phenylglycinamid 
• 113035-36-2 Nα,Nε-Bis(tert-butoxycarbonyl)-N-(2,6-dichlorbenzoyl)-N-phenyl-L-lysinamid 
• 113035-34-0 Nα-(tert-Butoxycarbonyl)-N-(2,6-dichlorbenzoyl)-N-phenyl-L-phenylalaninamid 
• 113035-37-3 Nα-(tert-Butoxycarbonyl)-N-(2,6-dichlorbenzoyl)-N-phenyl-L-asparaginamid 
• 113035-35-1 Nα-(tert-Butoxycarbonyl)-N-(2,6-dichlorbenzoyl)-N-phenyl-L-alaninamid 

Relevant articles and documents

Sodiation of Arenes and Heteroarenes in Continuous Flow

The first sodiations of (hetero)arenes in continuous flow using NaDA (sodium diisopropylamide) in Me2EtN are reported. This flow procedure enables sodiation of functionalized arenes and heteroarenes that decompose under batch-sodiation conditions. The resulting sodiated (hetero)arenes react instantly with various electrophiles, such as ketones, aldehydes, isocyanates, alkyl bromides, and disulfides, affording polyfunctionalized (hetero)arenes in high yields. Scale-up is possible without further optimization.

Continuous flow photochemistry as an enabling synthetic technology: Synthesis of substituted-6(5: H)-phenanthridinones for use as poly(ADP-ribose) polymerase inhibitors

Methods utilizing continuous flow photochemistry, an enabling synthetic technology, have been developed for the generation of phenanthridinones via an intramolecular photochemical cyclization of 2-chlorobenzamides for the purposes of generating poly(ADP-ribose) polymerase inhibitors. Herein we report 16 examples of a single-step flow photocyclization which produces substituted phenanthridinones in yields up to 99%, while a two-step method leads directly to phenanthridinones from 2-chlorobenzoyl chlorides and anilines via a novel continuous flow amidation/photocyclization protocol. Overall, the flow photocyclization reactions typically progress in good to excellent yields, and in a superior fashion to analogous batch methods, greatly enabling the drug discovery process.

Diacylamines - Perfect Acylating Agents for Peptide Synthesis

A new series of diacylamines containing N-protected amino acids have been synthesized.These diacylamines, possessing ortho-substituted benzoyl groups were found to be excellent acylating agents for peptide synthesis.In this reaction the 2,6-dichlorobenzoy