380423-89-2

Basic information

• Product Name: 1-(3,5-dichloro-benzyl)-piperidine-4-carboxylic acid amide
• CAS NO: 380423-89-2
• Molecular Weight: 287.189
• Mol File: 380423-89-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3,5-dichloro-benzyl)-piperidine-4-carboxylic acid amide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,5-dichloro-benzyl)-piperidine-4-carboxylic acid amide(380423-89-2)
• EPA Substance Registry System: 1-(3,5-dichloro-benzyl)-piperidine-4-carboxylic acid amide(380423-89-2)

Safety Data

• Hazardous Substances Data: 380423-89-2(Hazardous Substances Data)

Upstream product

• 39546-32-2 4-carboxamidopiperidine 
• 3290-06-0 1,3-dichloro-5-chloromethyl-benzene 

Downstream Products

• 380425-81-0 2-chloro-6-[4-[1-(3,5-dichlorobenzyl)]piperidinylamino]-9-cyclopentylpurine 
• 380424-52-2 4-amino-1-(3,5-dichlorobenzyl)piperidine 

Relevant articles and documents

The design and synthesis of purine inhibitors of CDK2. III

Cyclin-dependent kinases (CDKs) belong to a class of enzymes that control the ability of a cell to enter into and proceed through the cell division cycle. Using purine as a scaffold, we have synthesized a number of nanomolar inhibitors of CDK-2/cyclin E. In this report, the synthesis of a series of piperidine-substituted purine analogs will be presented, as well as some of their in vitro and in vivo biological effects.