380430-57-9 Usage
Description
4-(Methylsulfonylamino)phenylboronic acid is an organic compound with the molecular formula C7H11BNO4S. It is a versatile reagent in organic synthesis and has various applications in the pharmaceutical and chemical industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
4-(Methylsulfonylamino)phenylboronic acid is used as a reactant for the preparation of potent and selective inhibitors of IKK-β1 for the treatment of various diseases and conditions. It is also used as a reactant for the synthesis of inhibitors for the treatment of osteoporosis, which helps in the development of new therapeutic options for patients suffering from this bone disease.
Used in Chemical Industry:
4-(Methylsulfonylamino)phenylboronic acid is used as a reactant for the preparation of inhibitors of human farnesyl pyrophosphate synthase, an enzyme involved in the synthesis of cholesterol and other isoprenoid compounds. Inhibiting this enzyme can have potential applications in the treatment of diseases related to cholesterol metabolism.
Used in Organic Synthesis:
4-(Methylsulfonylamino)phenylboronic acid is used as a reactant in Suzuki-type Pd(0) coupling reactions, which are widely employed in the synthesis of various organic compounds, including 2-arylpurines as Cdk inhibitors. These inhibitors have potential applications in the development of new drugs for the treatment of cancer and other diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 380430-57-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,0,4,3 and 0 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 380430-57:
(8*3)+(7*8)+(6*0)+(5*4)+(4*3)+(3*0)+(2*5)+(1*7)=129
129 % 10 = 9
So 380430-57-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H10BNO4S/c1-14(12,13)9-7-4-2-6(3-5-7)8(10)11/h2-5,9-11H,1H3
380430-57-9Relevant articles and documents
ARYLSULFONAMIDE PYRIDINE-PYRIDINONE DERIVATIVES, PREPARATION OF SAME, AND THERAPEUTIC USE THEREOF
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Paragraph 0254, (2013/07/19)
The invention relates to pyridine-pyridinone derivatives general formula (I): in which R1, R2, R3, R4, n, n′, V, W, Y, Z, Ar are as defined in the description, and to their methods of preparation and their therapeutic applications.
