380542-05-2Relevant articles and documents
Structure-activity relationship study on col-003, a protein-protein interaction inhibitor between collagen and Hsp47
Yoshida, Masahito,Saito, Masazumi,Ito, Shinya,Ogawa, Koji,Goshima, Naoki,Nagata, Kazuhiro,Doi, Takayuki
, p. 220 - 226 (2020/11/26)
This study demonstrates the structure-activity relationship of Col-003, a potent collagen-heat-shock protein 47 (Hsp47) interaction inhibitor. Col-003 analogues were successfully synthesized by Pd(0)-catalyzed cross-coupling reactions of 5-bromosalicylald