380605-29-8

Basic information

• Product Name: 1-Cyclopropyl-1,3-dihydroimidazo[4,5-c]pyridine-2-one
• Synonyms: 1-Cyclopropyl-1,3-dihydroimidazo[4,5-c]pyridine-2-one;1-CYCLOPROPYL-1,3-DIHYDROIMIDAZO[4,5-C]PYRIDIN-2-ONE;1-Cyclopropyl-1,3-dihydro-2H-iMidazo[4,5-c]pyridin-2-one
• CAS NO: 380605-29-8
• Molecular Formula: C₉H₉N₃O
• Molecular Weight: 175.18726
• Mol File: 380605-29-8.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Density: 1.433g/cm³
• Refractive Index: 1.681
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-Cyclopropyl-1,3-dihydroimidazo[4,5-c]pyridine-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclopropyl-1,3-dihydroimidazo[4,5-c]pyridine-2-one(380605-29-8)
• EPA Substance Registry System: 1-Cyclopropyl-1,3-dihydroimidazo[4,5-c]pyridine-2-one(380605-29-8)

Safety Data

• Hazardous Substances Data: 380605-29-8(Hazardous Substances Data)

Usage

Description

1-Cyclopropyl-1,3-dihydroimidazo[4,5-c]pyridine-2-one is a chemical compound characterized by its unique structure, which features a cyclopropyl group and an imidazo[4,5-c]pyridine-2-one core. 1-Cyclopropyl-1,3-dihydroimidazo[4,5-c]pyridine-2-one has garnered interest due to its potential applications in various fields, particularly in the pharmaceutical industry.

Uses

1-Cyclopropyl-1,3-dihydroimidazo[4,5-c]pyridine-2-one is used as an inhibitor of human La protein, which plays a crucial role in the regulation of cellular processes. Its anti-viral activity makes it a promising candidate for the development of new antiviral therapies.
Used in Pharmaceutical Industry:
1-Cyclopropyl-1,3-dihydroimidazo[4,5-c]pyridine-2-one is used as a potential therapeutic agent for the treatment of viral infections. Its ability to inhibit the human La protein suggests that it may be effective in disrupting viral replication and reducing the severity of infections.
Additionally, the compound's unique structure and properties may also make it a candidate for further research and development in other areas of pharmaceuticals, such as the development of new drugs for various diseases and conditions. However, more research is needed to fully understand its potential applications and limitations in these areas.

InChI:InChI=1/C9H9N3O/c13-9-11-7-5-10-4-3-8(7)12(9)6-1-2-6/h3-6H,1-2H2,(H,11,13)

Upstream product

• 31872-62-5 4-methoxy-3-nitro-pyridine 
• 5435-54-1 4-hydroxy-3-nitropyridine 

Downstream Products

• 1383451-33-9 4-(5-bromo-2-((1-cyclopropyl-2-oxo-1H-imidazo[4,5-c]pyridin-3(2H)-yl)methyl)-1H-indol-1-yl)butyl 4-methylbenzensulfonate 

Relevant articles and documents

1-PYRAZOLYL, 5-, 6- DISUBSTITUTED INDAZOLE DERIVATIVES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

The present invention is directed to substituted certain 1-pyrazolyl, 5-, 6- disubstituted indazole derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, and ring A are as defined herein, which are potent inhibitors of LRRK2 kinase and may be useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease and other diseases and disorders described herein. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of diseases, such as Parkinson's disease, in which LRRK-2 kinase is involved.

QUINAZOLINE BASED RESPIRATORY SYNCYTIAL VIRUS INHIBITORS

Compounds of Formula (I), wherein R1, R2, R3, R4 and n are defined herein, are useful as inhibitors of RSV.

INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS

Indoles having inhibitory activity on RSV replication and having the formula I the prodrugs, N-oxides, addition salts, quaternary amines, metal complexes and stereochemically isomeric forms thereof; compositions containing these compounds as active ingredient and processes for preparing these compounds and compositions.