38081-61-7 Usage
Description
(4-methylphenyl)(piperidin-4-yl)methanol is a chemical compound with the molecular formula C14H19NO. It is a white to off-white solid with a molecular weight of 217.3 g/mol. (4-methylphenyl)(piperidin-4-yl)methanol is a derivative of piperidine and contains a phenyl group with a methyl substituent. Its properties make it suitable for use as a building block in organic synthesis and it has been investigated for its potential pharmacological properties, including its use as an analgesic and potential for treating substance abuse disorders.
Uses
Used in Pharmaceutical Synthesis:
(4-methylphenyl)(piperidin-4-yl)methanol is used as a building block in the synthesis of various pharmaceuticals and organic compounds. Its unique structure and properties make it a valuable component in the development of new drugs and therapeutic agents.
Used in Organic Synthesis:
(4-methylphenyl)(piperidin-4-yl)methanol is used as a key intermediate in the synthesis of complex organic compounds. Its versatility allows for its incorporation into a wide range of chemical reactions, facilitating the creation of diverse molecules with potential applications in various industries.
Used in Pain Management:
(4-methylphenyl)(piperidin-4-yl)methanol is used as an analgesic, helping to alleviate pain and discomfort. Its potential as a pain-relieving agent is currently being investigated, with the aim of developing new treatments for chronic and acute pain conditions.
Used in Substance Abuse Treatment:
(4-methylphenyl)(piperidin-4-yl)methanol has been investigated for its potential use in treating substance abuse disorders. Its pharmacological properties suggest that it may be effective in managing addiction and withdrawal symptoms, offering a new avenue for treatment and recovery.
Check Digit Verification of cas no
The CAS Registry Mumber 38081-61-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,0,8 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 38081-61:
(7*3)+(6*8)+(5*0)+(4*8)+(3*1)+(2*6)+(1*1)=117
117 % 10 = 7
So 38081-61-7 is a valid CAS Registry Number.
38081-61-7Relevant articles and documents
Syntheses and Binding Studies of New [(Aryl)(aryloxy)methyl]piperidine Derivatives and Related Compounds as Potential Antidepressant Drugs with High Affinity for Serotonin (5-HT) and Norepinephrine (NE) Transporters
Orjales, Aurelio,Mosquera, Ramón,Toledo, Antonio,Pumar, M. Carmen,García, Neftalí,Cortizo, Lourdes,Labeaga, Luis,Innerárity, Ana
, p. 5512 - 5532 (2007/10/03)
In a wide search program toward new, efficient, and fast-acting antidepressant drugs, we have prepared series of new compounds having an (aryl)(aryloxy)methyl moiety linked directly or through a methylene chain to different substituted and unsubstituted cycles (isoquinoline, piperazine, piperidine, tetrahydropyran, or cyclopentane). These compounds have been evaluated for their affinities for serotonin (5-HT) transporter (SERT) and 5-HT1A and 5-HT2A receptors. Racemic mixtures of 4-[(aryl)(aryloxy)methyl]piperidine derivatives showed much higher affinity values for SERT than fluoxetine and resulted in lack of affinity for 5-HT 1A and 5-HT2A receptors. Some of these racemic mixtures were resolved to their enantiomers and tested for binding to norepinephrine (NE) transporter (NET), dopamine (DA) transporter (DAT), and α2 receptor. Several of these enantiomers [(-)-15b, (-)-15j, (-)-15t, (+)-15u] displayed a dual binding profile with affinities for SERT and NET with K i i = 1.9 and 13.5 nM, respectively), and further pharmacological characterization is in progress for its evaluation as a antidepressant.
