380917-96-4

Basic information

• Product Name: 3-(2-cyanophenyl)-5-(2-pyridyl)-1,2-dihydropyridin-2-one
• Synonyms: 3-(2-cyanophenyl)-5-(2-pyridyl)-1,2-dihydropyridin-2-one
• CAS NO: 380917-96-4
• Molecular Weight: 273.294
• Mol File: 380917-96-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(2-cyanophenyl)-5-(2-pyridyl)-1,2-dihydropyridin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-cyanophenyl)-5-(2-pyridyl)-1,2-dihydropyridin-2-one(380917-96-4)
• EPA Substance Registry System: 3-(2-cyanophenyl)-5-(2-pyridyl)-1,2-dihydropyridin-2-one(380917-96-4)

Safety Data

• Hazardous Substances Data: 380917-96-4(Hazardous Substances Data)

Upstream product

• 18698-99-2 2-(2-cyanophenyl)acetic acid 
• 117197-16-7 2-(2-cyanophenyl)acetamide 
• 381248-05-1 5-(2-pyridyl)-3-bromo-2-methoxypyridine 

Downstream Products

• 380917-97-5 [14C]-Perampanel 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF PERAMPANEL

The present invention provides intermediates useful for the synthesis of Perampanel and processes employing said intermediates for preparing Perampanel. The invention also provides processes for making the intermediates, crystalline forms of the intermediates and the use of the crystalline forms for preparing Perampanel.

1,2-DIHYDROPYRIDINE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF

The present invention provides a novel compound having an excellent AMPA receptor inhibitory action and/or kainate inhibitory action. A compound represented by the following formula, a salt thereof or hydrates thereof. In the formula, Q indicates NH, O or S; and R1, R2, R3, R4 and R5 are the same as or different from each other and each indicates hydrogen atom, a halogen atom, a C1-6 alkyl group or a group represented by the formula -X-A (wherein X indicates a single bond, an optionally sbutituted C1-6 alkylene group etc.; and A indicates an optionally substituted C6-14 aromatic hydrocarbocyclic group or 5- to 14-membered aromatic heterocyclic group etc.).