38092-88-5

Basic information

• Product Name: 8-Dechloro-9-chloro-N-Methyl Desloratadine
• Synonyms: 8-Dechloro-9-chloro-N-Methyl Desloratadine;9-Chloro-6,11-dihydro-11-(1-Methyl-4-piperidinylidene)-;Desloratadine IMpurity 5
• CAS NO: 38092-88-5
• Molecular Formula: C20H21ClN2
• Molecular Weight: 324.84714
• Product Categories: Amines;Aromatics;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Amines, Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 38092-88-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-Dechloro-9-chloro-N-Methyl Desloratadine(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Dechloro-9-chloro-N-Methyl Desloratadine(38092-88-5)
• EPA Substance Registry System: 8-Dechloro-9-chloro-N-Methyl Desloratadine(38092-88-5)

Safety Data

• Hazardous Substances Data: 38092-88-5(Hazardous Substances Data)

Usage

Description

8-Dechloro-9-chloro-N-Methyl Desloratadine is an isomer of N-Methyl Desloratadine, a compound with antianaphylactic and antihistaminic activity. It is used as an impurity in Loratadine, a medication commonly used to treat allergies.

Uses

Used in Pharmaceutical Industry:
8-Dechloro-9-chloro-N-Methyl Desloratadine is used as a Loratadine impurity for the development and manufacturing of allergy medications. Its presence in Loratadine helps in understanding the purity and quality of the final product, ensuring the safety and efficacy of the medication.

Upstream product

• 63463-36-5 (1-methyl-4-piperidyl)magnesium chloride 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 31255-55-7 3-(4-chloro-phenethyl)-pyridine-2-carbonitrile 
• 32998-95-1 N-tert-butyl-3-methylpyridine-2-carboxamide 
• 3964-84-9 7-Chlor-10,11-dihydro-4-aza-5H-dibenzocyclohepten-5-on 
• 38089-91-7 9-chloro-11-(1-methyl-piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol 

Downstream Products

• 109537-11-3 4-(9-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine-1-carboxylic acid ethyl ester 
• 117811-13-9 desloratadine 

Relevant articles and documents

Dual Antagonists of Platelet Activating Factor and Histamine. Identification of Structural Requirements for Dual Activity of N-Acyl-4-(5,6-dihydro-11H-benzocycloheptapyridin-11-ylidene)piperidines

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