38119-33-4

Basic information

• Product Name: 7H-Purin-2-amine, 6-chloro-7-methyl-
• CAS NO: 38119-33-4
• Molecular Formula: C6H6ClN5
• Mol File: 38119-33-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 7H-Purin-2-amine, 6-chloro-7-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 7H-Purin-2-amine, 6-chloro-7-methyl-(38119-33-4)
• EPA Substance Registry System: 7H-Purin-2-amine, 6-chloro-7-methyl-(38119-33-4)

Safety Data

• Hazardous Substances Data: 38119-33-4(Hazardous Substances Data)

Upstream product

• 74-87-3 methylene chloride 
• 10310-21-1 2-Amino-6-chloropurin 
• 74-88-4 methyl iodide 

Downstream Products

• 7329-79-5 2-amino-6-mercapto-7-methylpurine 
• 104802-81-5 2-amino-6-methylthio-7-methylpurine 
• 116137-82-7 O⁶,7-dimethylguanine 

Relevant articles and documents

Regioselective alkylation reaction of purines under microwave irradiation

The alkylation of purines which is generally carried out after anion formation by treatment with a base and alkyl halide is complicated and in the best cases, mixtures of N-alkylated compounds are obtained. Purine derivatives can be acquired from alkylati

Tricyclic purine analogs derived from 2-amino-6-chloropurine and 2,6-diaminopurine and their methylated quaternary salts

A novel series of tricyclic, etheno-bridged purine analogs was sythesized from 2-amino-6-(substituted amino)-9-methylpurines by cyclization with chloroacetaldehyde, with particular focus on the regioselectivity of the cyclization reaction and fluorescence properties. The analogs as well as the starting purines were alkylated with iodomethane, affording a new class of quaternary salts with potential biological activity. Neither significant fluorescence nor cytostatic effect was found.

Synthesis of heteromine C from guanine

Heteromine C previously isolated from a Taipei folk medicine plant, has been synthesised for the first time by selective methylation reactions starting from guanine. Thermal rearrangement to 1-methylherbipoline takes place when heteromine C is heated. It is shown that treatment of O6,9- dimethylguanine with methyl iodide gives the O6,7,9-trimethylguaninium iodide with complete selectivity, while similar reaction on O6,7- dimethylguanine results in methylation both in the 3- and 9-position.