383424-00-8

Basic information

• Product Name: Ethanethioic acid, S-[3-(3-formylphenoxy)propyl] ester
• CAS NO: 383424-00-8
• Molecular Formula: C12H14O3S
• Molecular Weight: 238.307
• Mol File: 383424-00-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethanethioic acid, S-[3-(3-formylphenoxy)propyl] ester(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanethioic acid, S-[3-(3-formylphenoxy)propyl] ester(383424-00-8)
• EPA Substance Registry System: Ethanethioic acid, S-[3-(3-formylphenoxy)propyl] ester(383424-00-8)

Safety Data

• Hazardous Substances Data: 383424-00-8(Hazardous Substances Data)

Upstream product

• 100-83-4 meta-hydroxybenzaldehyde 
• 40359-32-8 3-allyloxy-benzaldehyde 
• 507-09-5 tiolacetic acid 
• 144707-69-7 3-(3'-bromopropyloxy)benzaldehyde 
• 10387-40-3 potassium thioacetate 

Relevant articles and documents

Tuning on and off chemical- And photo-activity of exfoliated MoSe2nanosheets through morphologically selective "soft" covalent functionalization with porphyrins

The covalent functionalization of 2D transition metal dichalcogenides (TMDCs) with organic molecules exploiting the thiol conjugation approach is still a very controversial topic. We have synthesized thiolated tetraphenyl porphyrins, with and without hydr

Solid- and solution-phase synthesis of vancomycin and vancomycin analogues with activity against vancomycin-resistant bacteria

Vancomycin, the prototypical member of the glycopeptide family of antibiotics, is a clinically used antibiotic employed against a variety of drug-resistant bacterial strains including methicillin-resistant Staphylococcus aureus (MRSA). The recent emergence of vancomycin resistance, viewed as a growing threat to public health, prompted us to initiate a program aimed at restoring the potency of this important antibiotic through chemical manipulation of the vancomycin structure. Herein, we describe the development of synthetic technology based on the design of a novel selenium safety catch linker, application of this technology to a solid-phase semisynthesis of vancomycin, and the solid- and solution-phase synthesis of vancomycin libraries. Biological evaluation of these compound libraries led to the identification of a number of in vitro highly potent antibacterial agents effective against vancomycin-resistant bacteria. In addition to aiding these investigations, the solid-phase chemistry described herein is expected to enhance the power of combinatorial chemistry and facilitate chemical biology and medicinal chemistry studies.