38401-67-1

Basic information

• Product Name: 5-(4-Methoxyphenyl)thiophene-2-carbaldehyde
• Synonyms: RARECHEM AK MA K024;RARECHEM AK MA K025;1-[5-(4-METHOXYPHENYL)-2-THIENYL]-1-ETHANONE;1-[5-(4-METHOXYPHENYL)-2-THIENYL]ETHANONE;5-(4-METHOXYPHENYL)THIOPHENE-2-CARBOXALDEHYDE;5-(4-METHOXYPHENYL)THIOPHENE-2-CARBALDEHYDE;5-(4-METHOXYPHENYL)-2-THIOPHENECARBALDEHYDE;AKOS BAR-0528
• CAS NO: 38401-67-1
• Molecular Formula: C₁₂H₁₀O₂S
• Molecular Weight: 218.28
• Mol File: 38401-67-1.mol
• Article Data: 30

Chemical Properties

• Melting Point: 118 °C
• Boiling Point: 375.8°C at 760 mmHg
• Flash Point: 181.1°C
• Appearance: /
• Density: 1.213g/cm³
• Vapor Pressure: 7.57E-06mmHg at 25°C
• Refractive Index: 1.613
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 5-(4-Methoxyphenyl)thiophene-2-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-Methoxyphenyl)thiophene-2-carbaldehyde(38401-67-1)
• EPA Substance Registry System: 5-(4-Methoxyphenyl)thiophene-2-carbaldehyde(38401-67-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 38401-67-1(Hazardous Substances Data)

Usage

General Description

5-(4-methoxyphenyl)thiophene-2-carbaldehyde is a chemical compound with a molecular formula of C12H10O2S. It belongs to the organic class of thiophene compounds, characterized by a five-membered ring containing four carbon atoms and a sulfur atom. Thiophenes are widely found in essential oils and often serve as the parent compound for various pharmaceutical drugs. The particular presence of the methoxyphenyl group and an aldehyde functional group in 5-(4-methoxyphenyl)thiophene-2-carbaldehyde allow it to exhibit interesting chemical properties that can be exploited in organic synthesis for diverse applications.

InChI:InChI=1/C12H10O2S/c1-14-10-4-2-9(3-5-10)12-7-6-11(8-13)15-12/h2-8H,1H3

Upstream product

• 98-03-3 thiophene-2-carbaldehyde 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 5720-07-0 4-methoxyphenylboronic acid 
• 4701-17-1 5-bromo-2-thiophencarboxaldehyde 
• 42545-43-7 2-(4-methoxyphenyl)thiophene 
• 75-27-4 bromodichloromethane 
• 464192-28-7 2-bromo-1,3-thiazole-5-carbaldehyde 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 107-20-0 2-chloroethanal 
• 14063-79-7 3-chloro-3-(4-methoxyphenyl)acrylaldehyde 
• 696-62-8 para-iodoanisole 
• 68-12-2 N,N-dimethyl-formamide 
• 38071-22-6 4,5-dibromothiophene-2-carboxaldehyde 

Downstream Products

• 1314022-93-9 ethyl 2-(4-methoxyphenyl)-4H-thieno[3,2-b]pyrrole-5-carboxylate 
• 1314022-94-0 2-(4-methoxy-phenyl)-4H-thieno[3,2-b]pyrrole-5-carboxylic acid 
• 1451254-00-4 1,3-diethyl-5-(5′-(4′′-methoxyphenylthiophen-2′-yl)-methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione 
• 1429099-05-7 1-(5-(4-methoxyphenyl)thiophen-2-yl)prop-1-ol 
• 1429097-56-2 1-{1-(5-(4-methoxyphenyl)thiophen-2-yl)propyl}-1H-imidazole 
• 1429097-58-4 4-[5-(1-imidazol-1-ylpropyl)thiophen-2-yl]phenol 
• 773870-69-2 (5-(4-methoxyphenyl)thiophene-2-yl)methanol 
• 42545-43-7 2-(4-methoxyphenyl)thiophene 

Relevant articles and documents

Regioselective double Suzuki couplings of 4,5-dibromothiophene-2-carboxaldehyde

Conditions have been identified that enable the one-pot double Suzuki coupling of 4,5-dibromothiophene-2-carboxaldehyde to proceed in good yield. The key to success in these reactions is the use of minimal amounts of water to avoid significant amounts of

Design, synthesis and evaluation of phenylthiazole and phenylthiophene pyrimidindiamine derivatives targeting the bacterial membrane

As the continuous rise in the incidence of antibiotic resistance, it is urgent to develop novel chemical scaffolds with antibacterial activities to control the spread of resistance to conventional antibiotics. In this study, a series of phenylthiazole and

Synthesis of an Air-Stable Pd(0) Catalyst Bearing Donor and Acceptor Phosphine Ligands

We synthesized a new Pd(0) complex bearing π-acceptor ligands and a σ-donor ligand and confirmed that it exhibits high air stability and catalytic activity in direct arylation reactions. Moreover, stoichiometric reactions of the complex revealed that the σ-donor ligand does not dissociate from the Pd center.