38447-82-4

Basic information

• Product Name: 2H-Thiopyran-4-ol, tetrahydro-4-methyl-
• CAS NO: 38447-82-4
• Molecular Formula: C6H12OS
• Mol File: 38447-82-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2H-Thiopyran-4-ol, tetrahydro-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Thiopyran-4-ol, tetrahydro-4-methyl-(38447-82-4)
• EPA Substance Registry System: 2H-Thiopyran-4-ol, tetrahydro-4-methyl-(38447-82-4)

Safety Data

• Hazardous Substances Data: 38447-82-4(Hazardous Substances Data)

Upstream product

• 1072-72-6 Tetrahydrothiopyran-4-one 
• 917-54-4 methyllithium 
• 185-73-9 1-oxa-6-thiaspiro<2.5>octane 
• 75-16-1 methylmagnesium bromide 
• 917-64-6 methyl magnesium iodide 

Relevant articles and documents

Scalable preparation of 4,4-disubstituted six-membered cyclic sulfones

We provide an account of synthetic strategies aimed at the efficient preparation of 4-amino-4-methyltetrahydro-2H-thiopyran 1,1-dioxide (3), an important cyclic sulfone building block for medicinal chemistry. A practical and scalable protocol has been developed that readily gives access to the title compound from commercially available and inexpensive starting materials. In addition, this novel approach has enabled the synthesis of various related 4,4-disubstituted cyclic sulfone derivatives that serve as valuable structural motifs for drug discovery.

Di(2-pyridyl) carbonate promoted alkoxycarbonylation of amines: A convenient synthesis of functionalized carbamates

The reaction of di(2-pyridyl) carbonate with a variety of alcohols including hindered secondary, tertiary and protected glycols afforded the corresponding mixed carbonate which was efficiently transformed into various carbamates in high yield under mild c