384820-56-8

Basic information

• Product Name: C₂₉H₂₇ClN₂O₃
• CAS NO: 384820-56-8
• Molecular Weight: 486.998
• Mol File: 384820-56-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₉H₂₇ClN₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₉H₂₇ClN₂O₃(384820-56-8)
• EPA Substance Registry System: C₂₉H₂₇ClN₂O₃(384820-56-8)

Safety Data

• Hazardous Substances Data: 384820-56-8(Hazardous Substances Data)

Upstream product

• 33522-95-1 noroxymorphone 
• 205676-17-1 2-(4-chlorophenyl)malondialdehyde 
• 384820-54-6 N-(2-methylallyl)oxymorphone 

Relevant articles and documents

Derivatives of 17-(2-methylallyl)-substituted noroxymorphone: variation of the delta address and its effects on affinity and selectivity for the delta opioid receptor.

In an effort to establish the importance of the N-(2-methylallyl) substituent in the noroxymorphone series, several derivatives have been synthesized, retaining that N-substituent and modifying the delta address moiety. A few compounds showed moderate binding affinity and selectivity for the delta receptor; none displayed a pharmacological profile as exceptional as N-(2-methylallyl)noroxymorphindole. A second study showed that 3-O-methylation of all derivatives decreases binding affinity. The present results indicate that only a combination of the N-(2-methylallyl) group and an indole delta address provided high selectivity for the delta receptor.