3850-33-7

Basic information

• Product Name: 2H-Isoindole-2-acetic acid, a-(1,1-dimethylethyl)-1,3-dihydro-1,3-dioxo-
• Synonyms: 3,3-dimethyl-2-phthalimido-butyric acid;2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3,3-dimethyl-butyric acid;N-Phthaloyl-tert-leucin;(+/-)-N-phthaloyl-tert-leucine
• CAS NO: 3850-33-7
• Molecular Formula: C14H15NO4
• Molecular Weight: 261.277
• Mol File: 3850-33-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: 190 - 190.5 °C
• Boiling Point: 419.7±28.0 °C(Predicted)
• Density: 1.313±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2H-Isoindole-2-acetic acid, a-(1,1-dimethylethyl)-1,3-dihydro-1,3-dioxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Isoindole-2-acetic acid, a-(1,1-dimethylethyl)-1,3-dihydro-1,3-dioxo-(3850-33-7)
• EPA Substance Registry System: 2H-Isoindole-2-acetic acid, a-(1,1-dimethylethyl)-1,3-dihydro-1,3-dioxo-(3850-33-7)

Safety Data

• Hazardous Substances Data: 3850-33-7(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 33105-81-6 2-amino-3,3-dimethylbutanoic acid 

Relevant articles and documents

Decarboxylative fluorination of aliphatic carboxylic acids via photoredox catalysis

The direct conversion of aliphatic carboxylic acids to the corresponding alkyl fluorides has been achieved via visible light-promoted photoredox catalysis. This operationally simple, redox-neutral fluorination method is amenable to a wide variety of carboxylic acids. Photon-induced oxidation of carboxylates leads to the formation of carboxyl radicals, which upon rapid CO2-extrusion and F? transfer from a fluorinating reagent yield the desired fluoroalkanes with high efficiency. Experimental evidence indicates that an oxidative quenching pathway is operable in this broadly applicable fluorination protocol.