38544-16-0 Usage
Description
2-(Benzyloxy)-5-chlorobenzaldehyde is a chemical compound with the molecular formula C14H11ClO2. It is a benzaldehyde derivative featuring a benzyl ether functional group attached to the second carbon atom of the benzaldehyde ring. The chlorine atom on the benzaldehyde ring imparts unique properties to this compound. It is widely used in organic synthesis and serves as a building block for creating various organic compounds. Additionally, it is utilized as an intermediate in the production of pharmaceuticals and agrochemicals, with potential applications in biotechnology, pharmaceuticals, and materials science.
Uses
Used in Organic Synthesis:
2-(Benzyloxy)-5-chlorobenzaldehyde is used as a key intermediate in organic synthesis for the preparation of a variety of organic compounds. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2-(Benzyloxy)-5-chlorobenzaldehyde is utilized as an intermediate in the synthesis of various drugs. Its presence in the molecular structure can contribute to the development of new pharmaceuticals with improved therapeutic properties.
Used in Agrochemical Development:
2-(Benzyloxy)-5-chlorobenzaldehyde also finds application in the agrochemical sector, where it is used as a building block for the development of new agrochemicals. Its unique chemical structure can lead to the creation of novel compounds with enhanced pesticidal or herbicidal activity.
Used in Biotechnology:
In the field of biotechnology, 2-(Benzyloxy)-5-chlorobenzaldehyde has potential applications in the development of new biologically active compounds. Its unique structure can be leveraged to create molecules with specific biological functions, contributing to advancements in biotechnological applications.
Used in Materials Science:
2-(Benzyloxy)-5-chlorobenzaldehyde is also employed in materials science for the development of new materials with specialized properties. Its incorporation into the molecular structure of these materials can lead to the creation of innovative materials with unique characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 38544-16-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,5,4 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 38544-16:
(7*3)+(6*8)+(5*5)+(4*4)+(3*4)+(2*1)+(1*6)=130
130 % 10 = 0
So 38544-16-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H11ClO2/c15-13-6-7-14(12(8-13)9-16)17-10-11-4-2-1-3-5-11/h1-9H,10H2
38544-16-0Relevant articles and documents
Exploring intermolecular contacts in multi-substituted benzaldehyde derivatives: X-ray, Hirshfeld surface and lattice energy analyses
Hosten, Eric C.,Hulushe, Siya T.,Louzada, Marcel,Manyeruke, Meloddy H.,Rigin, Sergei,Watkins, Gareth M.
, p. 16861 - 16874 (2020/05/18)
Crystal structures of six benzaldehyde derivatives (1-6) have been determined and their supramolecular networks were established by an X-ray crystallographic study. The study has shown that the compounds are linked by various intermolecular interactions s
3-Arylpropionylhydroxamic acid derivatives as Helicobacter pylori urease inhibitors: Synthesis, molecular docking and biological evaluation
Shi, Wei-Kang,Deng, Rui-Cheng,Wang, Peng-Fei,Yue, Qin-Qin,Liu, Qi,Ding, Kun-Ling,Yang, Mei-Hui,Zhang, Hong-Yu,Gong, Si-Hua,Deng, Min,Liu, Wen-Run,Feng, Qiu-Ju,Xiao, Zhu-Ping,Zhu, Hai-Liang
, p. 4519 - 4527 (2016/09/13)
Helicobacter pylori urease is involved in several physiologic responses such as stomach and duodenal ulcers, adenocarcinomas and stomach lymphomas. Thus, inhibition of urease is taken for a good chance to treat H. pylori-caused infections, we have therefore focused our efforts on seeking novel urease inhibitors. Here, a series of arylpropionylhydroxamic acids were synthesized and evaluated for urease inhibition. Out of these compounds, 3-(2-benzyloxy-5-chlorophenyl)-3-hydroxypropionylhydroxamic acid (d24) was the most active inhibitor with IC50of 0.15?±?0.05?μM, showing a mixed inhibition with both competitive and uncompetitive aspects. Non-linear fitting of kinetic data gives kinetics parameters of 0.13 and 0.12?μg·mL?1for Kiand Ki′, respectively. The plasma protein binding assays suggested that d24 exhibited moderate binding to human and rabbit plasma proteins.
Synthesis and evaluation of 3-hydroxy-3-phenylpropanoate ester-AZT conjugates as potential dual-action HIV-1 Integrase and Reverse Transcriptase inhibitors
Manyeruke, Meloddy H.,Olomola, Temitope O.,Majumder, Swarup,Abrahams, Shaakira,Isaacs, Michelle,Mautsa, Nicodemus,Mosebi, Salerwe,Mnkandhla, Dumisani,Hewer, Raymond,Hoppe, Heinrich C.,Klein, Rosalyn,Kaye, Perry T.
, p. 7521 - 7528 (2015/12/18)
Novel 3-hydroxy-3-phenylpropanoate ester-azidothymidine (AZT) conjugates have been prepared using Baylis-Hillman methodology, and their potential as dual-action HIV-1 Integrase and Reverse Transcriptase inhibitors has been explored using enzyme inhibition
