38561-68-1

Basic information

• Product Name: 4-Octenedioic acid
• Synonyms: 4-Octenedioic acid;cis-4-Octenedioic acid
• CAS NO: 38561-68-1
• Molecular Formula: C₈H₁₂O₄
• Molecular Weight: 172.18
• Mol File: 38561-68-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 373.11°C at 760 mmHg
• Flash Point: 193.63°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.501
• CAS DataBase Reference: 4-Octenedioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Octenedioic acid(38561-68-1)
• EPA Substance Registry System: 4-Octenedioic acid(38561-68-1)

Safety Data

• Hazardous Substances Data: 38561-68-1(Hazardous Substances Data)

Usage

General Description

4-Octenedioic acid, also known as sorbic acid, is a straight-chain unsaturated dicarboxylic acid with the chemical formula C8H12O4. It is a colourless crystalline solid that is highly soluble in water and has a characteristic sour taste. 4-Octenedioic acid is commonly used as a preservative in food and beverages due to its ability to inhibit the growth of mold, yeast, and fungi. It is often added to products such as cheese, wine, and baked goods to extend their shelf life and prevent spoilage. Additionally, it is used in cosmetic and personal care products for its antimicrobial properties. Despite its widespread use, 4-Octenedioic acid is generally considered safe for consumption and topical application in the prescribed amounts.

InChI:InChI=1/C8H12O4/c9-7(10)5-3-1-2-4-6-8(11)12/h1-2H,3-6H2,(H,9,10)(H,11,12)/b2-1-

Upstream product

• 4157-62-4 (E)-oct-4-ene-1,8-dinitrile 
• 54911-87-4 2-(4-Vinyloxy-hex-5-enyloxy)-tetrahydro-pyran 
• 54432-95-0 di-tert-butyl (Z)-oct-4-enedioate 
• 591-80-0 pent-4-enoic acid 
• 63521-92-6 4-pentenoic anhydride 
• 113882-48-7 pent-4-enoic acid benzyl ester 
• 19740-90-0 (Z)-9-oxabicyclo[6.1.0]non-4-ene 
• 5259-72-3 cyclo-octa-1,5-diene 
• 57042-08-7 Diethyl trans-hex-3-enedioate 
• 71655-17-9 (E)-3-hexen-1,6-diol 
• 59533-63-0 1,6-dibromo-trans-3-hexene 
• 54432-94-9 Z-4-octenedioic acid dimethylester 
• 1552-12-1 1,5-cis,cis-cyclooctadiene 
• 199856-14-9 hex-3-yne-1,1,6,6-tetracarboxylic acid 

Relevant articles and documents

The effect of vicinal difluorination on the conformation and potency of histone deacetylase inhibitors

Histone deacetylase enzymes (HDACs) are potential targets for the treatment of cancer and other diseases, but it is challenging to design isoform selective agents. In this work, we created new analogs of two established but non selective HDAC inhibitors. We decorated the central linker chains of the molecules with specifically positioned fluorine atoms in order to control the molecular conformations. The fluorinated analogs were screened against a panel of 11 HDAC isoforms, and minor differences in isoform selectivity patterns were observed.

IMPROVED OLEFIN METATHESIS CATALYSTS

The present invention refers to novel ruthenium-based catalysts for olefin metathesis reactions, particularly to fast initiating catalysts having stereoselective properties. In olefin metathesis reactions, the disclosed catalysts provide a high catalytic activity combined with the capability to generate higher yields of the olefin metathesis product.

The synthesis of 12-membered macrocycles containing a C1-C8 alkene unit via ring-closing metathesis

Model cross and ring-closing metathesis strategies toward the C1-C8-linear carbon skeleton are presented. The introduction of a four-atom tether enables the formation of 12-membered rings in good-to-excellent yields and stereoselectivity. Furthermore, the study revealed that the cross-metathesis approach and the formation of medium ring sizes via ring-closing metathesis are much less favorable.