38642-36-3

Basic information

• Product Name: 2,2-Dimethylpropionic acid (2R)-2,3,3aβ,9aβ-tetrahydro-6-oxo-2α-[(pivaloyloxy)methyl]-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3β-yl ester
• Synonyms: 2,2-Dimethylpropionic acid (2R)-2,3,3aβ,9aβ-tetrahydro-6-oxo-2α-[(pivaloyloxy)methyl]-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3β-yl ester
• CAS NO: 38642-36-3
• Molecular Formula: C₁₉H₂₆N₂O₇
• Molecular Weight: 394.41894
• Mol File: 38642-36-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2-Dimethylpropionic acid (2R)-2,3,3aβ,9aβ-tetrahydro-6-oxo-2α-[(pivaloyloxy)methyl]-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3β-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-Dimethylpropionic acid (2R)-2,3,3aβ,9aβ-tetrahydro-6-oxo-2α-[(pivaloyloxy)methyl]-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3β-yl ester(38642-36-3)
• EPA Substance Registry System: 2,2-Dimethylpropionic acid (2R)-2,3,3aβ,9aβ-tetrahydro-6-oxo-2α-[(pivaloyloxy)methyl]-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3β-yl ester(38642-36-3)

Safety Data

• Hazardous Substances Data: 38642-36-3(Hazardous Substances Data)

Upstream product

• 3736-77-4 2,2'-Anhydrouridine 
• 3282-30-2 pivaloyl chloride 
• 58-96-8 uridine 

Downstream Products

• 26929-65-7 2'-azido-2'-deoxyuridine 
• 3736-77-4 2,2'-Anhydrouridine 

Relevant articles and documents

Regioselective Mitsunobu Reaction of Partially Protected Uridine

Mitsunobu reaction of partially acylated uridine proceeds with high regioselectivity for intramolecular SN2 anhydro linkage closuring. Under the reaction conditions, an isomeric mixture of diacyl uridine derivatives with either free 2′- or 3′-hydroxyl group was transformed into a single cyclonucleosidic product, 2,2′-anhydro-3′,5′-di-O-acyluridine. This paper presents a possible mechanism of the reactions, the explanation of observed phenomenon based on semiempirical and density functional theory (DFT) calculations and possible utility of this synthetic pathway.