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38647-10-8

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  • Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one,3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6,10-dihydroxy-8b-methyl-6a-(1-methylethyl)-,(3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS,10S)-

    Cas No: 38647-10-8

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38647-10-8 Usage

Description

Tripdiolide is a naturally occurring compound derived from the plant Tripterygium wilfordii, which has been traditionally used in Chinese medicine. It possesses potent anti-inflammatory and anticancer properties, making it a promising candidate for pharmaceutical applications.

Uses

Used in Pharmaceutical Industry:
Tripdiolide is used as an anticancer agent for its ability to inhibit the growth and proliferation of various types of cancer cells. It targets multiple signaling pathways and exhibits cytotoxic effects, making it a potential therapeutic option for cancer treatment.
Tripdiolide is also used as an anti-inflammatory agent due to its ability to reduce inflammation and alleviate pain. It can be utilized in the development of medications for treating inflammatory diseases and conditions.
In addition to its direct applications, Tripdiolide can be further researched and developed for use in novel drug delivery systems to enhance its bioavailability, efficacy, and targeted delivery to specific cells or tissues.

Check Digit Verification of cas no

The CAS Registry Mumber 38647-10-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,6,4 and 7 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 38647-10:
(7*3)+(6*8)+(5*6)+(4*4)+(3*7)+(2*1)+(1*0)=138
138 % 10 = 8
So 38647-10-8 is a valid CAS Registry Number.
InChI:InChI=1/C20H24O7/c1-7(2)18-13(26-18)14-20(27-14)17(3)5-10(21)12-8(6-24-15(12)22)9(17)4-11-19(20,25-11)16(18)23/h7,9-11,13-14,16,21,23H,4-6H2,1-3H3/t9-,10-,11-,13-,14-,16+,17-,18-,19+,20+/m0/s1

38647-10-8Upstream product

38647-10-8Downstream Products

38647-10-8Relevant articles and documents

First total synthesis of tripdiolide

Zhou, Bing,Tang, Huanyu,Feng, Huijin,Li, Yuanchao

, p. 904 - 909 (2011)

The first total synthesis of tripdiolide 1 from the readily available abietic acid 3 in 22 steps is described and this synthesis furnishes a 5.8% overall yield of 1 with an average yield of 87%.

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