387335-31-1 Usage
Description
1H-2-Benzopyran-4-ol (9CI), commonly known as coumarin, is a fragrant organic chemical compound that is naturally found in various plants such as tonka beans, cinnamon, and grass varieties. It is characterized by its sweet, vanilla-like scent and is widely used in the production of pharmaceuticals, perfumes, and flavorings.
Uses
Used in Pharmaceutical Industry:
1H-2-Benzopyran-4-ol (9CI) is used as an active pharmaceutical ingredient for its medicinal properties. It is incorporated into various drug formulations due to its therapeutic benefits.
Used in Perfumery Industry:
1H-2-Benzopyran-4-ol (9CI) is used as a fixative and scent component in perfumes and fragrances, enhancing the longevity and complexity of the scents.
Used in Flavoring Industry:
1H-2-Benzopyran-4-ol (9CI) is used as a flavoring agent in food and beverages, imparting a sweet, vanilla-like taste and aroma.
However, it is important to note that excessive consumption of 1H-2-Benzopyran-4-ol (9CI) has been linked to liver toxicity. As a result, its use as a food additive is regulated in some countries, and its application in various industries is carefully monitored to ensure safety.
Check Digit Verification of cas no
The CAS Registry Mumber 387335-31-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,7,3,3 and 5 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 387335-31:
(8*3)+(7*8)+(6*7)+(5*3)+(4*3)+(3*5)+(2*3)+(1*1)=171
171 % 10 = 1
So 387335-31-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H8O2/c10-9-6-11-5-7-3-1-2-4-8(7)9/h1-4,6,10H,5H2
387335-31-1Relevant articles and documents
Keto - Enol/enolate equilibria in the isochroman-4-one system. Effect of a β-oxygen substituent
Chiang,Kresge,Meng,More O'Ferrall,Zhu
, p. 11562 - 11569 (2001)
The enol of 1-tetralone was generated flash photolytically, and rates of its ketonization were measured in aqueous HClO4 and NaOH solutions as well as in CH3CO2H, H2PO4-, (CH2OH)3CNH3+, and NH4+ buffers. The enol of isochroman-4-one was also generated, by hydrolysis of its potassium salt and trimethylsilyl ether, and rates of its ketonization were measured in aqueous HClO4 and NaOH. Rates of enolization of the two ketones were measured as well. Combination of the enolization and ketonization data for isochroman-4-one gave the keto - enol equilibrium constant pKE = 5.26, the acidity constant of the enol ionizing as an oxygen acid pQaE = 10.14, and the acidity constant of the ketone ionizing as a carbon acid pQaK = 15.40. Comparison of these results with those for 1-tetralone shows that the β-oxygen substituent in isochroman-4-one raises all three of these constants: KE by 2 orders of magnitude, QaE by not quite 1 order of magnitude, and QaK by nearly 3 orders of magnitude. The β-oxygen substituent also retards the rate of hydronium-ion-catalyzed ketonization by more than 3 orders of magnitude. The origins of these substituent effects are discussed.
